Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50019336
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant human DNA polymerase eta expressed in baculovirus expression system using primer/TAMRA-labeled reporter/BHQ2-labeled templa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM60996(MLS002153482 | Aurintricarboxylic acid | 5-[(3-car...)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human DNA polymerase eta expressed in baculovirus expression system using primer/TAMRA-labeled reporter/BHQ2-labeled templa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50445690(CHEMBL457821)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618208(CHEMBL5398631)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618204(CHEMBL5433463)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human DNA polymerase eta (1 to 437 residues) using 5'-TTT TTT TTG C-TAMRA-3' reporter/5'-(FAM-TTT)-GGGGGAAGGATTC-3' primer/5'-TCACGGAAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50445691(CHEMBL243677)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50330971(2-(3,4-dihydroxyphenyl)-7-hydroxy-5-meth-oxy-4H-ch...)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50240896(CHEMBL163316 | 3',4',5,7-tetrahydroxy-3-methoxyfla...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM7462(cid_5280863 | CHEMBL150 | 3,5,7-trihydroxy-2-(4-hy...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618205(CHEMBL5418159)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406067(CHEMBL5272459)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618203(CHEMBL4584525)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of 6xHis-tagged human DNA polymerase eta (1 to 437 residues) expressed in Escherichia coli BL21 DE3 assessed as displacement of reporter s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50240899(cid_5280862 | 5,7-Dihydroxy-2-(4-hydroxy-phenyl)-3...)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406112(CHEMBL5279962)
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50077325(7,3',4'-Trihydroxyflavone | 2-(3,4-dihydroxyphenyl...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50157555(2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-d...)
Affinity DataIC50: 3.05E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618213(CHEMBL3326852)
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406065(CHEMBL3326854)
Affinity DataIC50: 6.24E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406062(CHEMBL5280903)
Affinity DataIC50: 8.46E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406063(CHEMBL5271510)
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406066(CHEMBL5284680)
Affinity DataIC50: 8.75E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 9.24E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618212(CHEMBL5440374)
Affinity DataIC50: 9.83E+4nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406111(CHEMBL228623)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406064(CHEMBL594248)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618209(CHEMBL5411625)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618206(CHEMBL5409887)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618207(CHEMBL5435484)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406068(CHEMBL5281399)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50406110(CHEMBL5284676)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618214(CHEMBL5418637)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618210(CHEMBL5403947)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50338975(2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-chrome...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDNA polymerase eta(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50618211(CHEMBL5419567)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of C-terminal 6xHis-tagged human DNA polymerase eta (1 to 511 residues) expressed in Escherichia coli BL21 DE3 using 5'-IRD700-GCAGGTCGACT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed