Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50022328
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50030476(CHEMBL458603)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells co-expressed with pGL5-luc luciferase assessed as increase in CAR ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650888(PK-11195)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells co-expressed with pGL5-luc luciferase assessed as reduction in CA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650886(CHEMBL5632237)
Affinity DataEC50:  55nMAssay Description:Partial agonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells coexpressed with pGL5-luc luciferase measured after 1 to 4 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650888(PK-11195)
Affinity DataIC50: 245nMAssay Description:Inverse agonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells co-expressed with pGL5-luc luciferase assessed as reduction ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650885(CHEMBL5631778)
Affinity DataEC50:  6.96E+3nMAssay Description:Partial agonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells coexpressed with pGL5-luc luciferase measured after 1 to 4 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650887(CHEMBL5632832)
Affinity DataEC50:  1.06E+4nMAssay Description:Partial agonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells coexpressed with pGL5-luc luciferase measured after 1 to 4 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650884(CHEMBL1611121)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human CAR LBD expressed in human HepG2 cells incubated for 24 hrs in presence of CITCO by dual luciferase reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650888(PK-11195)
Affinity DataIC50: 6.98E+4nMAssay Description:Antagonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells co-expressed with pGL5-luc luciferase assessed as reduction in CA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
Charles University

Curated by ChEMBL
LigandPNGBDBM50650884(CHEMBL1611121)
Affinity DataIC50: 9.57E+4nMAssay Description:Antagonist activity at human CAR LBD (151 to 349 residues) expressed in HepG2 cells co-expressed with pGL5-luc luciferase assessed as reduction in CA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed