Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50021925
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataKi:  3nMAssay Description:Inhibition of recombinant SARS CoV-2 Wuhan-Hu-1 main protease extracted from Escherichia coli using Dabcyl-KTSAVLQSGFRKME-Edans as substrate incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646231(CHEMBL5593831)
Affinity DataKi:  8nMAssay Description:Inhibition of SARS CoV-2 main protease extracted from Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50405464(CHEMBL5270743)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant SARS CoV-2 main protease extracted from Escherichia coli BL21 (DE3) using MCA-AVLQSGFR-Lys (DNP)-Lys-NH2 as substrate by FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646230(CHEMBL5594068)
Affinity DataIC50: 22nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataIC50: 30nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM420297(med.21724, Compound 62 | peptidomimetic aldehydes ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of SARS CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate preincubated for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50619399(CHEMBL5404334)
Affinity DataIC50: 72nMAssay Description:Inhibition of SARS CoV-2 main protease extracted from Escherichia coli BL21 (DE3) using Dabcyl-KTSAVLQSGFRKME-Edans as substrate preincubated for 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM682841(US20240208970, Compound 49 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 77nMAssay Description:Inhibition of SARS CoV-2 main protease extracted from Escherichia coli BL21 (DE3) T1R competent cells using DABCYL-Lys-HCoV-SARS Replicase Polyprotei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50166940(NP-031112 | NP-12 | Tideglusib | med.21724, Compou...)
Affinity DataIC50: 300nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646216(CHEMBL5593580)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646229(CHEMBL5591288)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646227(CHEMBL5595865)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646219(CHEMBL5590459)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646221(CHEMBL5591539)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646218(CHEMBL5593903)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646220(CHEMBL5595272)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646222(CHEMBL5592599)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646214(CHEMBL5591010)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646228(CHEMBL1620799)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646217(CHEMBL5584157)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646225(CHEMBL5591320)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646224(CHEMBL5592993)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646226(CHEMBL5593882)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646215(CHEMBL5591923)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Peking University

Curated by ChEMBL
LigandPNGBDBM50646223(CHEMBL5593227)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of SARS CoV-2 main proteaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed