Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50021046
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM451097(US10676485, Example 7)
Affinity DataKi: <0.0100nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM470606(US10821115, Example 10 | US11224601, Example 10)
Affinity DataKi:  0.0150nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636298(CHEMBL5542691)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50514202(CHEMBL4446369 | US11274105, Example 179)
Affinity DataKi:  0.0620nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636299(CHEMBL5542775)
Affinity DataKi:  0.0760nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50519034(CHEMBL4572199)
Affinity DataKd:  0.190nMAssay Description:Binding affinity to human Mcl-1 assessed as dissociation constant by Surface Plasmon Resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <0.5nMAssay Description:Binding affinity to Bcl-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <0.5nMAssay Description:Binding affinity to human recombinant Bcl-2 assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM333146(US10196404, Example 1 | Compound I | US10196404, E...)
Affinity DataIC50: 0.720nMAssay Description:Inhibition of N-terminal GST-tagged human Mcl-1expressed in Escherichia coli by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKi: <1nMAssay Description:Binding affinity to human recombinant Bcl-2 assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKi: <1nMAssay Description:Binding affinity to Bcl-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50519614(CHEMBL4439276)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50519034(CHEMBL4572199)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by Fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM333146(US10196404, Example 1 | Compound I | US10196404, E...)
Affinity DataKi:  6nMAssay Description:Binding affinity to human Mcl-1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636296(CHEMBL5542342)
Affinity DataKi:  6nMAssay Description:Binding affinity to human Mcl-1 assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636302(CHEMBL5567775)
Affinity DataIC50: 10nMAssay Description:Inhibition of Mcl-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50519022(CHEMBL4472351)
Affinity DataKi:  19nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636295(CHEMBL5567254)
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST-tagged human Mcl-1expressed in Escherichia coli by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636297(CHEMBL5538127)
Affinity DataKi:  26nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by Fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50158355(CHEMBL3781822 | US10858316, Compound 3bl)
Affinity DataKi:  31nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50158355(CHEMBL3781822 | US10858316, Compound 3bl)
Affinity DataKi:  31nMAssay Description:Binding affinity to recombinant human Mcl-1 assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636303(CHEMBL5563923)
Affinity DataIC50: 40nMAssay Description:Inhibition of Mcl-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636294(CHEMBL5542971)
Affinity DataIC50: 42nMAssay Description:Inhibition of N-terminal GST-tagged human Mcl-1expressed in Escherichia coli by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50303802(CHEMBL4169380)
Affinity DataKd:  150nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50303802(CHEMBL4169380)
Affinity DataKd:  150nMAssay Description:Binding affinity to N-terminal His-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant by Surface plasmon r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM333146(US10196404, Example 1 | Compound I | US10196404, E...)
Affinity DataKi:  170nMAssay Description:Binding affinity to N-terminal GST-tagged human Mcl-1 expressed in Escherichia coli assessed as inhibition constant by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636301(CHEMBL5559516)
Affinity DataIC50: 300nMAssay Description:Inhibition of Mcl-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636300(CHEMBL5555190)
Affinity DataIC50: 300nMAssay Description:Inhibition of Mcl-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant Mcl-1 by Surface Plasmon Resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM451097(US10676485, Example 7)
Affinity DataKi: >468nMAssay Description:Binding affinity to Bfl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM451097(US10676485, Example 7)
Affinity DataKi: >468nMAssay Description:Binding affinity to Bcl-W (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  490nMAssay Description:Binding affinity to recombinant human Mcl-1 assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  490nMAssay Description:Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM451097(US10676485, Example 7)
Affinity DataKi:  599nMAssay Description:Binding affinity to Bcl-2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM451097(US10676485, Example 7)
Affinity DataKi: >660nMAssay Description:Binding affinity to Bcl-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM67473(SR-03000000694-1 | 3-chloranyl-1-benzothiophene-2-...)
Affinity DataKi:  1.31E+3nMAssay Description:Binding affinity to N-terminal His-tagged human recombinant Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50587654(CHEMBL5181796)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Mcl-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636296(CHEMBL5542342)
Affinity DataKi:  3.75E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluorescence polarization assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50636296(CHEMBL5542342)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity to Bcl-XL (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  5.33E+3nMAssay Description:Binding affinity to Bfl-1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  8.19E+3nMAssay Description:Binding affinity to Bcl-W (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50519614(CHEMBL4439276)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human Bcl-2 assessed as inhibition constant SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  2.38E+4nMAssay Description:Binding affinity to human recombinant Bcl-2 assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  3.30E+4nMAssay Description:Binding affinity to Bcl-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50424718(CHEMBL2314512)
Affinity DataKi:  6.80E+4nMAssay Description:Binding affinity to N-terminal His-tagged human recombinant Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed