Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50021951
TargetCyclin-dependent kinase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609166(CHEMBL5280928)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to CDK4 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609166(CHEMBL5280928)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to CDK6 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of GST-tagged full length wildtype CDK7 (unknown origin) extracted from baculovirus infected Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataKd:  0.330nMAssay Description:Binding affinity to CDK7 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624664(CHEMBL5432801)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 13(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50584000(CHEMBL4877117)
Affinity DataKd:  4.90nMAssay Description:Binding affinity to CDK13 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609166(CHEMBL5280928)
Affinity DataKi:  5.90nMAssay Description:Binding affinity to CDK2 (unknown origin) extracted from insect cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50593922(CHEMBL5199065)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50646414(CHEMBL5592751)
Affinity DataIC50: 8nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50646415(CHEMBL5595312)
Affinity DataEC50:  9nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incuabted for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609166(CHEMBL5280928)
Affinity DataKi:  9.60nMAssay Description:Binding affinity to CDK9 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM148264(US8962630, 74 | Ribociclib | LEE011 | Kisqali | 7-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553488(CHEMBL4743691)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant full length His-tagged CDK9/cyclin T1 extracted from Insect cells using biotinylated peptide biotin-Ttds-YISPLKSPYKIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM59227(Pyrazolopyrimidone analog, RGB-286147)
Affinity DataEC50:  12nMAssay Description:Inhibition of 6His-tagged wild type CDK12/cyclin K (unknown origin) infected in insect cells incuabted for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50466842(CHEMBL1615221)
Affinity DataEC50:  16nMAssay Description:Inhibition of CDK12/cyclin K (unknown origin) in HEK293T cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50526790(CHEMBL4555799)
Affinity DataIC50: 23nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50: 29nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 8(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 33nMAssay Description:Inhibition of full length C-terminal CDK8 (unknown origin) extracted from Bac-to-Bac baculovirus expression system infected in Sf9 cells measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM148264(US8962630, 74 | Ribociclib | LEE011 | Kisqali | 7-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50609166(CHEMBL5280928)
Affinity DataKi:  47nMAssay Description:Binding affinity to CDK1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624664(CHEMBL5432801)
Affinity DataIC50: 51nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM154576(K03861 (1))
Affinity DataKd:  53nMAssay Description:Binding affinity to CDK2 (unknown origin) extracted from baculovirus infected Sf9 cells assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50528812(CHEMBL4582951)
Affinity DataIC50: 80nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50584000(CHEMBL4877117)
Affinity DataKd:  98nMAssay Description:Binding affinity to CDK12 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant CDK12/cyclin K extracted from baculovirus infected insect cells incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50528812(CHEMBL4582951)
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
Affinity DataIC50: 230nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50646414(CHEMBL5592751)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 13(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
Affinity DataIC50: 620nMAssay Description:Inhibition of CDK13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50: 620nMAssay Description:Inhibition of GST-tagged full length wildtype CDK7 (unknown origin) extracted from baculovirus infected Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 690nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50110178(CHEMBL3603847 | US10787436, Compound I-23)
Affinity DataIC50: 890nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50528812(CHEMBL4582951)
Affinity DataIC50: 910nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50553488(CHEMBL4743691)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human recombinant GST-tagged CDK2/Cyclin E extracted from Sf9 cells using biotinylated peptide biotin-Ttds-YISPLKSPYKISEG as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of CDK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 5(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of CDK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50584000(CHEMBL4877117)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CDK9 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50584000(CHEMBL4877117)
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to CDK6 (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50584000(CHEMBL4877117)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK4 (unknown origin) by DiscoverX Kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50584000(CHEMBL4877117)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin) by DiscoverX Kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50584000(CHEMBL4877117)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1 (unknown origin) by DiscoverX Kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50485599(CHEBI:34457 | 5-NITRO-2-PHENYLPROPYLAMINOBENZOIC A...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of N-terminal GST-tagged human CDK2 (1 to 298 residues) extracted from Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM60927(ANS | BDBM50126831 | 1-anilinonaphthalene-8-sulfon...)
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to N-terminal GST-tagged human CDK2 (1 to 298 residues) extracted from Escherichia coli BL21 (DE3) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)