Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50022220
TargetSignal transducer and activator of transcription 3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50366597(2-Acetylfuranonaphthoquinone | BBI-608 | Napabucas...)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of IL-6-induced STAT3 activation in HEK293-STAT3-Luc2P cell line assessed as decrease in phosphorylated STAT3 (p-STAT3 Tyr705) level measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50649543(CHEMBL5619286)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of IL-6-induced STAT3 activation in HEK293-STAT3-Luc2P cell line assessed as decrease in phosphorylated STAT3 (p-STAT3 Tyr705) level measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50649543(CHEMBL5619286)
Affinity DataKd:  8.30E+3nMAssay Description:Inhibition of recombinant GST-tagged STAT3 (unknown origin) assessed as dissociation constant by Surface plasmon resonance (SPR) assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed