Found 4 Enz. Inhib. hit(s) with Target = 'Signal transducer and activator of transcription 3' and Ligand = 'BDBM50366597' TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Kindai University
Curated by ChEMBL
Kindai University
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of IL-6 induced STAT3 phosphorylation at Tyr705 residue in human MCF7 cells preincubated for 1 hr followed by IL-6 stimulation and measure...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Kindai University
Curated by ChEMBL
Kindai University
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of IL-6 induced STAT3 transcriptional activity in human HEK293 cells expressing SIE-luc2P preincubated for overnight followed by IL-6 stim...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Kindai University
Curated by ChEMBL
Kindai University
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Inhibition of STAT3 phosphorylation at Y705 in human MDA-MB-231 cells after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
Kindai University
Curated by ChEMBL
Kindai University
Curated by ChEMBL
Affinity DataEC50: 1.90E+3nMAssay Description:Inhibition of STAT3 phosphorylation at Y705 in human MDA-MB-231 cells assessed as reduction in ratio of phosphorylated STAT3 to total STAT3 level aft...More data for this Ligand-Target Pair
