Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50022651
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 176589BDBM176589(US9120761, 3)
Affinity DataKd:  0.210nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568532BDBM50568532(CHEMBL4742157)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 418817BDBM418817(US10450297, Example 317 | US10450297, Example 318 ...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 418817BDBM418817(US10450297, Example 317 | US10450297, Example 318 ...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378913BDBM50378913(Apg 2449 | Apg-2449 | APG2449)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 134067BDBM134067(US8846689, 69 | US20250154134, Compound BI853520)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574638BDBM50574638(CHEMBL4862976)
Affinity DataIC50: 1nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318884BDBM50318884(CHEMBL1084546 | CHEMBL2430359 | N-methyl-N-(3-((2-...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440659BDBM50440659(CHEMBL2430358)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetALK tyrosine kinase receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378913BDBM50378913(Apg 2449 | Apg-2449 | APG2449)
Affinity DataIC50: 1.60nMAssay Description:In vitro cell based assay for measuring the IC50 values of osteoblast resorption.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 245641BDBM245641(US9428508, 96)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193811BDBM50193811(CHEMBL3951811)
Affinity DataIC50: 2nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 245641BDBM245641(US9428508, 96)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetALK tyrosine kinase receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 245641BDBM245641(US9428508, 96)
Affinity DataIC50: 2.40nMAssay Description:in vitro cell based assay for measuring the IC50 values of osteoblast resorption.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50574638BDBM50574638(CHEMBL4862976)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50269948BDBM50269948(PF-228 | 6-(4-(3-(methylsulfonyl)benzylamino)-5-(t...)
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378913BDBM50378913(Apg 2449 | Apg-2449 | APG2449)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334594BDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50520571BDBM50520571(CHEMBL4447794)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378920BDBM50378920(CHEMBL6133002)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 245641BDBM245641(US9428508, 96)
Affinity DataIC50: 11nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378921BDBM50378921(CHEMBL6078426)
Affinity DataIC50: 14nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50318884BDBM50318884(CHEMBL1084546 | CHEMBL2430359 | N-methyl-N-(3-((2-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378922BDBM50378922(CHEMBL6078135)
Affinity DataIC50: 16nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378914BDBM50378914(CHEMBL6120660)
Affinity DataIC50: 19nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378921BDBM50378921(CHEMBL6078426)
Affinity DataIC50: 20nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378918BDBM50378918(CHEMBL6091944)
Affinity DataIC50: 21nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378917BDBM50378917(CHEMBL4634065)
Affinity DataIC50: 26nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetInsulin receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334594BDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 44nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378915BDBM50378915(CHEMBL6133434)
Affinity DataIC50: 45nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378919BDBM50378919(CHEMBL4303724)
Affinity DataIC50: 50nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378916BDBM50378916(CHEMBL6078070)
Affinity DataIC50: 79nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378916BDBM50378916(CHEMBL6078070)
Affinity DataIC50: 86nMAssay Description:Inhibition of TACE by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378922BDBM50378922(CHEMBL6078135)
Affinity DataIC50: 132nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334594BDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438033BDBM50438033(CHEMBL2409605)
Affinity DataIC50: 370nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetFocal adhesion kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50438033BDBM50438033(CHEMBL2409605)
Affinity DataIC50: 400nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetProtein-tyrosine kinase 2-beta(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378918BDBM50378918(CHEMBL6091944)
Affinity DataIC50: 623nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetInsulin receptor(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378915BDBM50378915(CHEMBL6133434)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed