Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50022654
Affinity DataEC50: 58nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 390nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 460nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 460nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.12E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Tested for Farnesyl Transferase Inhibition to displace 50% of radiolabeled Farnesyltransferase inhibitors from Farnesyltransferase in v-Ha-ras-transf...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at ghrelin receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+3nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.30E+3nMAssay Description:Inhibition of BACE1 expressed in HEK cells by cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of BACE1 expressed in HEK cells by cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Inhibition of BACE1 by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Inhibition of BACE1 expressed in HEK cells by cell-based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-42 production by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.60E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.60E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned kappa opioid receptor by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.30E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of BACE1-mediated amyloid beta (1 to 40) production after 48 hrs by cell based HTRF immunoassayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 4.44E+3nMAssay Description:Antagonist activity at human ERbeta LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.50E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 4.71E+3nMAssay Description:Agonist activity at human PPARdelta LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 4.94E+3nMAssay Description:Antagonist activity at human ERRalpha LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 4.97E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 5.05E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of BACE1 expressed in HEK cells by cell-based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 5.27E+3nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.55E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.68E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of GSK3beta-mediated CRMP-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"
Curated by ChEMBL
University of Naples "Federico II"
Curated by ChEMBL
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of BACE1 assessed as inhibition of amyloid beta-40 production by cell based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.30E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
