Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50023093
TargetGenome polyprotein(Hepacivirus C)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658997BDBM50658997(CHEMBL6169147)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGenome polyprotein(Hepacivirus C)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336504BDBM50336504((2R,3aR,11aS,12aR,14aR)-N-(cyclopropylsulfonyl)-2-...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGenome polyprotein(Hepacivirus C)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336504BDBM50336504((2R,3aR,11aS,12aR,14aR)-N-(cyclopropylsulfonyl)-2-...)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25121BDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataIC50: 0.830nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402023BDBM50402023(BI 6727 | VOLASERTIB)
Affinity DataIC50: 0.870nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331094BDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetVascular endothelial growth factor receptor 1(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331094BDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331094BDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGenome polyprotein(Hepacivirus C)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658997BDBM50658997(CHEMBL6169147)
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGenome polyprotein(Hepacivirus C)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658997BDBM50658997(CHEMBL6169147)
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331094BDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGenome polyprotein(Hepacivirus C)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336504BDBM50336504((2R,3aR,11aS,12aR,14aR)-N-(cyclopropylsulfonyl)-2-...)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGenome polyprotein(Hepacivirus C)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1517BDBM1517(CHEMBL37628 | 2-ethyl-7-methyl-2,4,9,15-tetraazatr...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGenome polyprotein(Hepacivirus C)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 12311BDBM12311(SCH 503034 | (1R,5S)-N-[3-Amino-1-(cyclobutylmethy...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
Target72 kDa type IV collagenase(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354624BDBM50354624(CHEMBL1834422 | US9951035, ND-322 (2) | US10357546...)
Affinity DataKi:  24nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 3(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331094BDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetFibroblast growth factor receptor 2(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331094BDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 1(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331094BDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetFibroblast growth factor receptor 4(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331094BDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1517BDBM1517(CHEMBL37628 | 2-ethyl-7-methyl-2,4,9,15-tetraazatr...)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1434BDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658995BDBM50658995(CHEMBL6168538)
Affinity DataKd:  55nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGenome polyprotein(Hepacivirus C)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658996BDBM50658996(CHEMBL6120459)
Affinity DataKi:  66nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331094BDBM50331094(4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-meth...)
Affinity DataIC50: 85nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658995BDBM50658995(CHEMBL6168538)
Affinity DataKd:  131nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGTPase KRas(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658995BDBM50658995(CHEMBL6168538)
Affinity DataKd:  364nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetMatrix metalloproteinase-9(Human)
Monash University (Malaysia Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50354624BDBM50354624(CHEMBL1834422 | US9951035, ND-322 (2) | US10357546...)
Affinity DataKi:  870nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed