Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50023684
TargetEukaryotic initiation factor 4A-I(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50196926BDBM50196926(Rocaglamide | CHEMBL438139 | US10085988, Compound ...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full length 6xHis-tagged EIF4A1 (unknown origin) by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEukaryotic initiation factor 4A-I(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666748BDBM50666748(CHEMBL6177866)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant full length 6xHis-tagged EIF4A1 (unknown origin) by FP assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProbable global transcription activator SNF2L2(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469330BDBM50469330(CHEMBL4295096 | US11958846, Example 7)
Affinity DataIC50: 5nMAssay Description:Inhibition of SMARCA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335583BDBM50335583(silvestrol | CHEMBL555196)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant full length 6xHis-tagged EIF4A1 (unknown origin) by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 646442BDBM646442(US11878973, Example 123)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal Hexa-histidine-tagged human recombinant WRN helicase domain (517 to 945 residues) extracted from Baculovirus infected Sf9 ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666750BDBM50666750(CHEMBL6166922)
Affinity DataIC50: 140nMAssay Description:Inhibition of N-terminal Hexa-histidine-tagged human recombinant WRN helicase domain (517 to 945 residues) extracted from Baculovirus infected Sf9 ce...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666750BDBM50666750(CHEMBL6166922)
Affinity DataIC50: 140nMAssay Description:Inhibition of N-terminal WRN (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRecQ-like DNA helicase BLM(Human)
University of Toronto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666749BDBM50666749(CHEMBL6174927)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of BLM (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed