Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50023241
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325671BDBM50325671(CHEMBL8996 | eriodicryol | (S)-2-(3,4-dihydroxyphe...)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to GFP-tagged FTO (unknown origin) assessed as dissociation constant by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325671BDBM50325671(CHEMBL8996 | eriodicryol | (S)-2-(3,4-dihydroxyphe...)
Affinity DataKd:  3.24E+3nMAssay Description:Binding affinity to GFP-tagged FTO (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325671BDBM50325671(CHEMBL8996 | eriodicryol | (S)-2-(3,4-dihydroxyphe...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108879BDBM50108879((2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-d...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50157555BDBM50157555(2-(3,4-dihydroxyphenyl)-4H-chromen-4-one | 3',4'-d...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7459BDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26656BDBM26656(5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chrome...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7461BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7457BDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-on...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7460BDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15236BDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7458BDBM7458(Naringenin, 18 | 5,7-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660896BDBM50660896(CHEMBL4785388)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26658BDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23411BDBM23411(5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50077313BDBM50077313(7-Hydroxy-chromen-4-one | 7-hydroxychromone | CHEM...)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009001BDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7462BDBM7462(cid_5280863 | CHEMBL150 | 3,5,7-trihydroxy-2-(4-hy...)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081950BDBM50081950(6-hydroxy-2-phenyl-4H-chromen-4-one | NSC-26744 | ...)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26664BDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50084978BDBM50084978(Kaempferide | Kaempferol 4'-methyl ether | CHEMBL4...)
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 644028BDBM644028(US11866416, Compound SN-II-78)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049391BDBM50049391(norizalpinin | 3,5,7-trihydroxy-2-phenyl-4H-benzop...)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049385BDBM50049385(5-Hydroxy-2-phenyl-chromen-4-one | 5-hydroxy-flavo...)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7461BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
Affinity DataKd:  2.15E+4nMAssay Description:Binding affinity to GFP-tagged FTO (unknown origin) assessed as dissociation constant by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15236BDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataKd:  3.40E+4nMAssay Description:Binding affinity to GFP-tagged FTO (unknown origin) assessed as dissociation constant by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Anhui Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24783BDBM24783(4H-chromen-4-one | chromone, 12)
Affinity DataIC50: 8.98E+4nMAssay Description:Inhibition of His-tagged N-terminal FTO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed