Compile Data Set for Download or QSAR
Report error Found 457 Enz. Inhib. hit(s) with all data for entry = 8650
LigandPNGBDBM410256((rac)-N-(3-(1,2,4,4a,5,6-hexahydro-[1,4]oxazino[4,...)
Affinity DataIC50: 0.00100nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410342(N-(3-((4aR,6R)-6-Hydroxy-1,2,4,4a,5,6-hexahydro-[1...)
Affinity DataIC50: 0.00200nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410277((rac)-N-(3-(6-hydroxy-6-methyl-1,2,4,4a,5,6-hexahy...)
Affinity DataIC50: 0.00200nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410356(rac-trans-2-(1,1-Difluoroethyl)-N-(3-(5-(hydroxyme...)
Affinity DataIC50: 0.00200nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410350(US10377770, Example 110)
Affinity DataIC50: 0.00200nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410352(US10377770, Example 112)
Affinity DataIC50: 0.00200nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410384(US10377770, Example 144)
Affinity DataIC50: 0.00200nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410387(US10377770, Example 147)
Affinity DataIC50: 0.00300nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410381(US10377770, Example 141)
Affinity DataIC50: 0.00400nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410393(US10377770, Example 153)
Affinity DataIC50: 0.00500nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410362(rac-trans-N-(3-(5-(Hydroxymethyl)-1,2,4,4a,5,6-hex...)
Affinity DataIC50: 0.00500nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410363(rac-trans-N-(3-(5-(Hydroxymethyl)-1,2,4,4a,5,6-hex...)
Affinity DataIC50: 0.00500nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410357(2-(1,1-Difluoroethyl)-N-(3-((4aR,5R)-5-(hydroxymet...)
Affinity DataIC50: 0.00500nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410358(2-(1,1-Difluoroethyl)-N-(3-((4aR,5R)-5-(hydroxymet...)
Affinity DataIC50: 0.00500nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410231((trans)-2-(1,1-difluoroethyl)-N-(3-(6-hydroxy-1,2,...)
Affinity DataIC50: 0.00500nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410351(US10377770, Example 111)
Affinity DataIC50: 0.00500nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410207((trans)-N-(3-(6-hydroxy-1,2,4,4a,5,6-hexahydro-[1,...)
Affinity DataIC50: 0.00600nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410293(N-(3-(5,5-bis(hydroxymethyl)-1,2,4,4a,5,6-hexahydr...)
Affinity DataIC50: 0.00600nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410306(2-(1,1-difluoroethyl)-N-(3-(5-(hydroxymethyl)-1,2,...)
Affinity DataIC50: 0.00600nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410349(US10377770, Example 109)
Affinity DataIC50: 0.00600nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410223(US10377770, Example 12)
Affinity DataIC50: 0.00700nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410399(US10377770, Example 159)
Affinity DataIC50: 0.00700nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410281(US10377770, Example 44 | US10377770, Example 43)
Affinity DataIC50: 0.00800nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410274((rac)-(cis)-N-(3-(6-hydroxy-1,2,4,4a,5,6-hexahydro...)
Affinity DataIC50: 0.00800nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410353(US10377770, Example 113)
Affinity DataIC50: 0.00800nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410268((trans)-N-(3-(6-methoxy-1,2,4,4a,5,6-hexahydro-[1,...)
Affinity DataIC50: 0.00800nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410361(N-(5-((4aR,5R)-5-(Hydroxymethyl)-1,2,4,4a,5,6-hexa...)
Affinity DataIC50: 0.00900nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410300((rac)-N-(3-(5-(hydroxymethyl)-1,2,4,4a,5,6-hexahyd...)
Affinity DataIC50: 0.00900nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410364(US10377770, Example 124)
Affinity DataIC50: 0.00900nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410380(US10377770, Example 140)
Affinity DataIC50: 0.00900nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410269(US10377770, Example 34)
Affinity DataIC50: 0.00900nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410383(US10377770, Example 143)
Affinity DataIC50: 0.00900nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410279(US10377770, Example 42 | US10377770, Example 41)
Affinity DataIC50: 0.0100nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410299(2-(1,1-difluoroethyl)-N-(4-methyl-3-(2,4,4a,6-tetr...)
Affinity DataIC50: 0.0100nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410359(rac-trans-N-(5-(5-(Hydroxymethyl)-1,2,4,4a,5,6-hex...)
Affinity DataIC50: 0.0100nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410218(US10377770, Example 11 | US10377770, Example 9)
Affinity DataIC50: 0.0100nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410398(US10377770, Example 158)
Affinity DataIC50: 0.0100nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410298(2-(1,1-difluoroethyl)-N-(4-methyl-3-(2,4,4a,6-tetr...)
Affinity DataIC50: 0.0110nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410373(US10377770, Example 133)
Affinity DataIC50: 0.0110nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410406(US10377770, Example 166)
Affinity DataIC50: 0.0110nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410360(N-(5-((4aR,5R)-5-(Hydroxymethyl)-1,2,4,4a,5,6-hexa...)
Affinity DataIC50: 0.0110nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410392(US10377770, Example 152)
Affinity DataIC50: 0.0110nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410355(US10377770, Example 115)
Affinity DataIC50: 0.0110nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410346(US10377770, Example 106)
Affinity DataIC50: 0.0120nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410386(US10377770, Example 146)
Affinity DataIC50: 0.0120nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410413(US10377770, Example 173)
Affinity DataIC50: 0.0120nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410348(US10377770, Example 108)
Affinity DataIC50: 0.0130nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410273(2-(1,1-difluoroethyl)-N-(3-(6-methoxy-1,2,4,4a,5,6...)
Affinity DataIC50: 0.0130nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410389(US10377770, Example 149)
Affinity DataIC50: 0.0130nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

LigandPNGBDBM410294((rac)-N-(4-methyl-3-(2,4,4a,6-tetrahydro-1H-spiro[...)
Affinity DataIC50: 0.0130nMAssay Description:The activity of a compound according to the present invention can be assessed by well-known in vitro & in vivo methods. Raf inhibition data provided ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
US Patent

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