Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 9751
TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485849BDBM485849(US10946019, Example 4)
Affinity DataEC50:  200nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485851BDBM485851(US10946019, Example 5)
Affinity DataEC50:  300nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485954BDBM485954(US10946019, Example 46)
Affinity DataEC50:  700nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485848BDBM485848(US10946019, Example 3)
Affinity DataEC50:  900nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485938BDBM485938(US10946019, Example 42)
Affinity DataEC50:  1.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50346093BDBM50346093(4-(5-isopropyl-6-methyl-2-phenylpyrimidin-4-ylamin...)
Affinity DataEC50:  1.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50346092BDBM50346092(4-(6-methyl-2-phenyl-5-propylpyrimidin-4-ylamino)b...)
Affinity DataEC50:  1.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485870BDBM485870(US10946019, Example 16)
Affinity DataEC50:  2.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485868BDBM485868(US10946019, Example 14)
Affinity DataEC50:  2.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485898BDBM485898(US10946019, Example 30)
Affinity DataEC50:  2.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485941BDBM485941(US10946019, Example 45)
Affinity DataEC50:  2.50E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485886BDBM485886(US10946019, Example 26)
Affinity DataEC50:  4.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 50346091BDBM50346091(4-(5-ethyl-6-methyl-2-phenylpyrimidin-4-ylamino)be...)
Affinity DataEC50:  5.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485921BDBM485921(US10946019, Example 32)
Affinity DataEC50:  5.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485885BDBM485885(US10946019, Example 25)
Affinity DataEC50:  7.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485874BDBM485874(US10946019, Example 23)
Affinity DataEC50:  7.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485871BDBM485871(US10946019, Example 19)
Affinity DataEC50:  1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485869BDBM485869(US10946019, Example 15)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485933BDBM485933(US10946019, Example 39)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485926BDBM485926(US10946019, Example 36)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485914BDBM485914(US10946019, Example 31)
Affinity DataEC50:  1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485892BDBM485892(US10946019, Example 29)
Affinity DataEC50:  1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485872BDBM485872(US10946019, Example 20)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485940BDBM485940(US10946019, Example 44)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485864BDBM485864(US10946019, Example 10)
Affinity DataEC50: >2.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485847BDBM485847(US10946019, Example 1)
Affinity DataEC50: >5.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485939BDBM485939(US10946019, Example 43)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485937BDBM485937(US10946019, Example 41)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485928BDBM485928(US10946019, Example 37)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485922BDBM485922(US10946019, Example 35)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485861BDBM485861(US10946019, Example 9)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485856BDBM485856(US10946019, Example 6)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 485875BDBM485875(US10946019, Example 24)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent