Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 11066
TargetProteasome subunit alpha type-6(Human)
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 588478BDBM588478(US11542283, Compound IV-9 | (R)-N-(2,5-dichloroben...)
Affinity DataIC50: 4.86nMAssay Description:The proteasome used in the present invention is human erythrocyte 20S proteasome, and the enzyme, fluorescent substrate and test buffer are all purch...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetProteasome subunit alpha type-6(Human)
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50516758BDBM50516758(CHEMBL4444471 | US11542283, Compound V-9A)
Affinity DataIC50: 5.69nMAssay Description:The proteasome used in the present invention is human erythrocyte 20S proteasome, and the enzyme, fluorescent substrate and test buffer are all purch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetProteasome subunit alpha type-6(Human)
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 588482BDBM588482(US11542283, Compound V-9B | (R)-N-(2,5-dichloroben...)
Affinity DataIC50: 6.60nMAssay Description:The proteasome used in the present invention is human erythrocyte 20S proteasome, and the enzyme, fluorescent substrate and test buffer are all purch...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetProteasome subunit alpha type-6(Human)
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50462603BDBM50462603(CHEMBL4248209 | US11542283, Compound V-8A)
Affinity DataIC50: 7.02nMAssay Description:The proteasome used in the present invention is human erythrocyte 20S proteasome, and the enzyme, fluorescent substrate and test buffer are all purch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetProteasome subunit alpha type-6(Human)
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50462621BDBM50462621(CHEMBL1813256 | MLN-9708 | US11542283, Compound ML...)
Affinity DataIC50: 7.47nMAssay Description:The proteasome used in the present invention is human erythrocyte 20S proteasome, and the enzyme, fluorescent substrate and test buffer are all purch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetProteasome subunit alpha type-6(Human)
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50462625BDBM50462625(CHEMBL4243375 | US11542283, Compound IV-8)
Affinity DataIC50: 7.52nMAssay Description:The proteasome used in the present invention is human erythrocyte 20S proteasome, and the enzyme, fluorescent substrate and test buffer are all purch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetProteasome subunit alpha type-6(Human)
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 588480BDBM588480(US11542283, Compound V-8B | (S)-N-(2,5-dichloroben...)
Affinity DataIC50: 8.20nMAssay Description:The proteasome used in the present invention is human erythrocyte 20S proteasome, and the enzyme, fluorescent substrate and test buffer are all purch...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent

TargetProteasome subunit alpha type-6(Human)
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50069989BDBM50069989(CHEMBL325041 | (R)-3-methyl-1-((S)-3-phenyl-2-(pyr...)
Affinity DataIC50: 9.92nMAssay Description:The proteasome used in the present invention is human erythrocyte 20S proteasome, and the enzyme, fluorescent substrate and test buffer are all purch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent