Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 207 Enz. Inhib. hit(s) with all data for entry = 11349
TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280366(2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...)
Affinity DataIC50:  2.70nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280370(2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...)
Affinity DataIC50:  3.70nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280369(2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...)
Affinity DataIC50:  3.70nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280365(4-{[2-(5-chloro-2-fluorophenyl)-5-cyclopropylpyrid...)
Affinity DataIC50:  4.80nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280366(2-(5-chloro-2-fluorophenyl)-5-cyclopropyl-N-{1H-py...)
Affinity DataIC50:  6.10nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280352(N-(2-aminoethyl)-4-[[2-(5-chloro-2-fluoro-phenyl)-...)
Affinity DataIC50:  6.80nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280369(2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{7H-...)
Affinity DataIC50:  8.20nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280340((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...)
Affinity DataIC50:  8.60nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280360(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropenyl-4-p...)
Affinity DataIC50:  10.3nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280365(4-{[2-(5-chloro-2-fluorophenyl)-5-cyclopropylpyrid...)
Affinity DataIC50:  10.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280363(2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{1H-pyr...)
Affinity DataIC50:  10.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280352(N-(2-aminoethyl)-4-[[2-(5-chloro-2-fluoro-phenyl)-...)
Affinity DataIC50:  11nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280360(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropenyl-4-p...)
Affinity DataIC50:  11.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280348(N-(2-amino-2-oxo-ethyl)-4-[[2-(5-chloro-2-fluoro-p...)
Affinity DataIC50:  11.7nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280341((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-...)
Affinity DataIC50:  13nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280348(N-(2-amino-2-oxo-ethyl)-4-[[2-(5-chloro-2-fluoro-p...)
Affinity DataIC50:  15.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280340((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...)
Affinity DataIC50:  15.7nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280341((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-...)
Affinity DataIC50:  16.2nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280363(2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{1H-pyr...)
Affinity DataIC50:  16.4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280356(4-[[2-amino-6-(5-chloro-2-fluoro-phenyl)-3-isoprop...)
Affinity DataIC50:  16.9nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280345((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...)
Affinity DataIC50:  17.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280370(2-(5-chloro-2-fluorophenyl)-5-(propan-2-yl)-N-{1H-...)
Affinity DataIC50:  17.7nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  20.4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280346(4-[[2-(5-chloro-2-fluoro-phenyl)-5-methoxy-4-pyrid...)
Affinity DataIC50:  23.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280364(2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{7H-pyr...)
Affinity DataIC50:  23.7nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280347(N-(2-acetamidoethyl)-4-[[2-(5-chloro-2-fluoro-phen...)
Affinity DataIC50:  23.9nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280355(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50:  24.7nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280364(2-(3-fluoropyridin-2-yl)-5-(propan-2-yl)-N-{7H-pyr...)
Affinity DataIC50:  26.4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280361(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropenyl-4-p...)
Affinity DataIC50:  28.1nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280339((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-...)
Affinity DataIC50:  28.1nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280345((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...)
Affinity DataIC50:  30.4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280338((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-...)
Affinity DataIC50:  31.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50:  32.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280356(4-[[2-amino-6-(5-chloro-2-fluoro-phenyl)-3-isoprop...)
Affinity DataIC50:  33.1nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280344((S)-4-(2-(5-chloro-2-fluorophenyl)-5-ethylpyridin-...)
Affinity DataIC50:  33.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280351(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50:  34.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280350(4-[[2-(5-chloro-2-fluoro-phenyl)-5-(1-methoxy-1-me...)
Affinity DataIC50:  40.1nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280361(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropenyl-4-p...)
Affinity DataIC50:  40.2nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280349((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...)
Affinity DataIC50:  42.2nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280339((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-...)
Affinity DataIC50:  42.4nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280347(N-(2-acetamidoethyl)-4-[[2-(5-chloro-2-fluoro-phen...)
Affinity DataIC50:  45.1nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280338((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-...)
Affinity DataIC50:  45.2nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280350(4-[[2-(5-chloro-2-fluoro-phenyl)-5-(1-methoxy-1-me...)
Affinity DataIC50:  50.8nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM608828(Synthesis of 4-[[2-(5-chloro-2-fluoro-phenyl)-5-is...)
Affinity DataIC50:  53.9nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280355(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50:  56.7nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280357(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropenyl-4-p...)
Affinity DataIC50:  65.3nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280346(4-[[2-(5-chloro-2-fluoro-phenyl)-5-methoxy-4-pyrid...)
Affinity DataIC50:  71.5nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280368(2-(5-chloro-2-fluorophenyl)-5-(prop-1-en-2-yl)-N-[...)
Affinity DataIC50:  77.3nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetTGF-beta receptor type-1(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280367(4-{[2-(5-chloro-2-fluorophenyl)-5-(pyrrolidin-1-yl...)
Affinity DataIC50:  78.8nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetActivin receptor type-1B(Human)
Medivation Technologies

US Patent
LigandPNGBDBM280344((S)-4-(2-(5-chloro-2-fluorophenyl)-5-ethylpyridin-...)
Affinity DataIC50:  86.8nMAssay Description:Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ3 family of Ser/Thr kinases. The kinases ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


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