Compile Data Set for Download or QSAR
Report error Found 200 Enz. Inhib. hit(s) with all data for entry = 1306
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633338BDBM633338(US20190276450, Example 17.5)
Affinity DataEC50:  5nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633336BDBM633336(US20190276450, Example 17.3)
Affinity DataEC50:  8nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633289BDBM633289(US20190276450, Example 3.2)
Affinity DataEC50:  14nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633317BDBM633317(US20190276450, Example 12b.2)
Affinity DataEC50:  15nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633269BDBM633269(US20190276450, Example 1b.5)
Affinity DataEC50:  18nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633312BDBM633312(US20190276450, Example 12.5)
Affinity DataEC50:  22nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633360BDBM633360(US20190276450, Example 25)
Affinity DataEC50:  25nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633266BDBM633266(US20190276450, Example 1b.2)
Affinity DataEC50:  25nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633332BDBM633332(US20190276450, Example 17)
Affinity DataEC50:  31nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633288BDBM633288(US20190276450, Example 3)
Affinity DataEC50:  35nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633313BDBM633313(US20190276450, Example 12.6)
Affinity DataEC50:  39nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633280BDBM633280(US20190276450, Example 2.8)
Affinity DataEC50:  42nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633263BDBM633263(US20190276450, Example 1.2)
Affinity DataEC50:  45nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633319BDBM633319(US20190276450, Example 12b.4)
Affinity DataEC50:  45nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633298BDBM633298(US20190276450, Example 6)
Affinity DataEC50:  50nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633361BDBM633361(US20190276450, Example 26)
Affinity DataEC50:  50nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633305BDBM633305(US20190276450, Example 11)
Affinity DataEC50:  52nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633318BDBM633318(US20190276450, Example 12b.3)
Affinity DataEC50:  56nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633261BDBM633261(US20190276450, Example 1)
Affinity DataEC50:  59nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633316BDBM633316(US20190276450, Example 12a.3)
Affinity DataEC50:  66nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633352BDBM633352(US20190276450, Example 22.5)
Affinity DataEC50:  72nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633344BDBM633344(US20190276450, Example 21)
Affinity DataEC50:  80nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633303BDBM633303(US20190276450, Example 9)
Affinity DataEC50:  85nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633326BDBM633326(US20190276450, Example 14.6)
Affinity DataEC50:  87nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633349BDBM633349(US20190276450, Example 22.2)
Affinity DataEC50:  89nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633302BDBM633302(US20190276450, Example 8)
Affinity DataEC50:  90nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633304BDBM633304(US20190276450, Example 10)
Affinity DataEC50:  91nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633359BDBM633359(US20190276450, Example 24)
Affinity DataEC50:  92nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633357BDBM633357(US20190276450, Example 22.10)
Affinity DataEC50:  92nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633310BDBM633310(US20190276450, Example 12.3)
Affinity DataEC50:  94nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633274BDBM633274(US20190276450, Example 2.3)
Affinity DataEC50:  96nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633299BDBM633299(US20190276450, Example 6.2)
Affinity DataEC50:  103nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633283BDBM633283(US20190276450, Example 2.11)
Affinity DataEC50:  104nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633295BDBM633295(US20190276450, Example 5)
Affinity DataEC50:  111nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633350BDBM633350(US20190276450, Example 22.4 | US20190276450, Examp...)
Affinity DataEC50:  112nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633307BDBM633307(US20190276450, Example 11.2)
Affinity DataEC50:  124nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633271BDBM633271(US20190276450, Example 2)
Affinity DataEC50:  126nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633286BDBM633286(US20190276450, Example 2a.3)
Affinity DataEC50:  127nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633337BDBM633337(US20190276450, Example 17.4)
Affinity DataEC50:  127nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633353BDBM633353(US20190276450, Example 22.6)
Affinity DataEC50:  130nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633324BDBM633324(US20190276450, Example 14.4)
Affinity DataEC50:  134nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633342BDBM633342(US20190276450, Example 20)
Affinity DataEC50:  137nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633291BDBM633291(US20190276450, Example 4)
Affinity DataEC50:  137nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633268BDBM633268(US20190276450, Example 1b.4)
Affinity DataEC50:  142nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633335BDBM633335(US20190276450, Example 17.2)
Affinity DataEC50:  144nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633347BDBM633347(US20190276450, Example 22)
Affinity DataEC50:  146nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633325BDBM633325(US20190276450, Example 14.5)
Affinity DataEC50:  146nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633350BDBM633350(US20190276450, Example 22.4 | US20190276450, Examp...)
Affinity DataEC50:  147nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633296BDBM633296(US20190276450, Example 5.2)
Affinity DataEC50:  156nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Abbvie

US Patent
LigandChemical structure of BindingDB Monomer ID 633293BDBM633293(US20190276450, Example 4.3)
Affinity DataEC50:  174nMAssay Description:IL-12 is known to transduce its signal through IL-12 receptor via Jak2 and/or Tyk2. For that reason, the activity against Tyk2/Jak2 was measured by d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2023
Entry Details
US Patent

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