Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 11799
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 0.820nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 1nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 1.20nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 1.35nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 1.48nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 1.80nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 2.03nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 2.30nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 2.5nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 2.75nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 2.78nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 3.29nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 3.40nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 4.09nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 4.30nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 5.80nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 6nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
3D Structure (crystal)TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 6.23nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 6.34nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 7.20nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 13nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 17.7nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 18nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 35nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 35nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
Affinity DataEC50: 43nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 43nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 70nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 71.8nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 90.9nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 114nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
Affinity DataEC50: 147nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 150nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 400nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 480nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
Affinity DataEC50: 770nMAssay Description:To evaluate the anti-HSV activity of 1, 17 or Brequinar by plaque reduction assays (PRA), Vero cells were seeded in 24-well plates at a density of 70...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 2.21E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 2.21E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 2.76E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 3.94E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 5.20E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 6.98E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Drug Discovery and Clinic
US Patent
Drug Discovery and Clinic
US Patent
Affinity DataIC50: 7.20E+3nMAssay Description:The enzymatic inhibition assay was optimized for being performed on a 96 well plate and to achieve higher throughput. For each well of the plate a to...More data for this Ligand-Target Pair
