Compile Data Set for Download or QSAR
Report error Found 181 Enz. Inhib. hit(s) with all data for entry = 12192
TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685327(US20240239774, Example 63)
Affinity DataIC50: 0.455nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685332(US20240239774, Example 68)
Affinity DataIC50: 0.460nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685299(US20240239774, Example 35)
Affinity DataIC50: 0.826nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685304(US20240239774, Example 40)
Affinity DataIC50: 1.5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607672(CHEMBL5220723 | US20240239774, Example 82)
Affinity DataIC50: 1.60nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685367(US20240239774, Example 103)
Affinity DataIC50: 2nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685369(US20240239774, Example 105)
Affinity DataIC50: 2nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607679(CHEMBL5218615 | US20240239774, Example 80)
Affinity DataIC50: 2nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607678(CHEMBL5218878 | US20240239774, Example 76)
Affinity DataIC50: 2nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685388(US20240239774, Example 124)
Affinity DataIC50: 2nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607680(CHEMBL5218702 | US20240239774, Example 77)
Affinity DataIC50: 2.40nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685350(US20240239774, Example 86)
Affinity DataIC50: 3nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607686(CHEMBL5219830 | US20240239774, Example 133)
Affinity DataIC50: 3nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607676(CHEMBL5218698 | US20240239774, Example 78)
Affinity DataIC50: 3nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685389(US20240239774, Example 125)
Affinity DataIC50: 3nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685306(US20240239774, Example 42)
Affinity DataIC50: 3.5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685303(US20240239774, Example 39)
Affinity DataIC50: 3.80nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685348(US20240239774, Example 84)
Affinity DataIC50: 4nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685390(US20240239774, Example 126)
Affinity DataIC50: 4nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607672(CHEMBL5220723 | US20240239774, Example 82)
Affinity DataIC50: 4.20nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685302(US20240239774, Example 38)
Affinity DataIC50: 4.70nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607673(CHEMBL5220895 | US20240239774, Example 88)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685386(US20240239774, Example 122)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685360(US20240239774, Example 96)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685394(US20240239774, Example 130)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685426(US20240239774, Example 162)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685420(US20240239774, Example 156)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607674(CHEMBL5220347 | US20240239774, Example 123)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685419(US20240239774, Example 155)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685432(US20240239774, Example 168)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685399(US20240239774, Example 135)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685402(US20240239774, Example 138)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607683(CHEMBL5219579 | US20240239774, Example 132)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685395(US20240239774, Example 131)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685429(US20240239774, Example 165)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685408(US20240239774, Example 144)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685343(US20240239774, Example 79)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685409(US20240239774, Example 145)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685372(US20240239774, Example 108)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685353(US20240239774, Example 107 | US20240239774, Exampl...)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607682(CHEMBL5220685 | US20240239774, Example 139)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607685(CHEMBL5220647 | US20240239774, Example 141)
Affinity DataIC50: 5nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685353(US20240239774, Example 107 | US20240239774, Exampl...)
Affinity DataIC50: 6nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685301(US20240239774, Example 37)
Affinity DataIC50: 6nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685421(US20240239774, Example 157)
Affinity DataIC50: 6nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685400(US20240239774, Example 136)
Affinity DataIC50: 7nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607674(CHEMBL5220347 | US20240239774, Example 123)
Affinity DataIC50: 7.10nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM50607675(CHEMBL5219922 | US20240239774, Example 120)
Affinity DataIC50: 8nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685305(US20240239774, Example 41)
Affinity DataIC50: 8nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetAdenylate cyclase type 10(Human)
Cornell University; Tri-Institutional Therapeutics Discovery Institue, Inc.

US Patent
LigandPNGBDBM685428(US20240239774, Example 164)
Affinity DataIC50: 8nMAssay Description:Assays for sAC activity using purified protein were performed in 100 ul reactions containing 4 mM MgCl2, 2 mM CaCl2, 1 mM ATP, 40 mM NaHCO3, 50 mM Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

Displayed 1 to 50 (of 181 total ) | Next | Last >>
Jump to: