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Report error Found 79 Enz. Inhib. hit(s) with all data for entry = 6412
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127560BDBM127560(US8791100, 58)
Affinity DataIC50: 0.100nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127573BDBM127573(US8791100, 71)
Affinity DataIC50: 0.100nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127572BDBM127572(US8791100, 70)
Affinity DataIC50: 0.100nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127506BDBM127506(US8791100, 4)
Affinity DataIC50: 0.200nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127567BDBM127567(US8791100, 65)
Affinity DataIC50: 0.200nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127542BDBM127542(US8791100, 40)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127531BDBM127531(US8791100, 29)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127511BDBM127511(US8791100, 9)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127586BDBM127586(US8791100, 84)
Affinity DataIC50: 0.400nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127508BDBM127508(US8791100, 6)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127557BDBM127557(US8791100, 55)
Affinity DataIC50: 0.5nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127581BDBM127581(US8791100, 79)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127535BDBM127535(US8791100, 33)
Affinity DataIC50: 0.600nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127570BDBM127570(US8791100, 68)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127588BDBM127588(US8791100, 87 | US8791100, 86)
Affinity DataIC50: 0.700nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127580BDBM127580(US8791100, 78)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127541BDBM127541(US8791100, 39)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127530BDBM127530(US8791100, 28)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127545BDBM127545(US8791100, 43)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127536BDBM127536(US8791100, 34)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127571BDBM127571(US8791100, 69)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127534BDBM127534(US8791100, 32)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127569BDBM127569(US8791100, 67)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127524BDBM127524(US8791100, 22)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127540BDBM127540(US8791100, 38)
Affinity DataIC50: 0.800nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127505BDBM127505(US8791100, 3)
Affinity DataIC50: 0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127532BDBM127532(US8791100, 30)
Affinity DataIC50: 0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127564BDBM127564(US8791100, 62)
Affinity DataIC50: 0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127554BDBM127554(US8791100, 52)
Affinity DataIC50: 0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127587BDBM127587(US8791100, 85)
Affinity DataIC50: 0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127556BDBM127556(US8791100, 54)
Affinity DataIC50: 0.900nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127544BDBM127544(US8791100, 42)
Affinity DataIC50: 1nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127525BDBM127525(US8791100, 23)
Affinity DataIC50: 1nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127533BDBM127533(US8791100, 31)
Affinity DataIC50: 1nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127523BDBM127523(US8791100, 21)
Affinity DataIC50: 1nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127565BDBM127565(US8791100, 63)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127574BDBM127574(US8791100, 72)
Affinity DataIC50: 1.10nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127509BDBM127509(US8791100, 7)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127561BDBM127561(US8791100, 59)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127547BDBM127547(US8791100, 45)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127588BDBM127588(US8791100, 87 | US8791100, 86)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127568BDBM127568(US8791100, 66)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127575BDBM127575(US8791100, 73)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127550BDBM127550(US8791100, 53 | US8791100, 48)
Affinity DataIC50: 1.20nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127543BDBM127543(US8791100, 41)
Affinity DataIC50: 1.30nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127548BDBM127548(US8791100, 46)
Affinity DataIC50: 1.30nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127510BDBM127510(US8791100, 8)
Affinity DataIC50: 1.5nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127516BDBM127516(US8791100, 14)
Affinity DataIC50: 1.5nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127563BDBM127563(US8791100, 61)
Affinity DataIC50: 1.60nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetSphingosine 1-phosphate receptor 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 127512BDBM127512(US8791100, 10)
Affinity DataIC50: 1.60nMT: 2°CAssay Description:The assay measures intracellular changes of Ca2+ mediated by the synthetic probing agonist 3-{[2-(2-Trifluoromethyl-biphenyl-4-yl)-benzo[b]thiophen-5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

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