Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 7129
TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92485BDBM92485(CDE-066 | US9120744, CDE-066)
Affinity DataKd:  3.10nMpH: 5.0 T: 2°CAssay Description:To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92486BDBM92486(CDE-082 | US9120744, CDE-082)
Affinity DataKd:  5.30nMpH: 5.0 T: 2°CAssay Description:To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175526BDBM175526(US9120744, CDE-002)
Affinity DataIC50: 10nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175528BDBM175528(US9120744, CDE-004)
Affinity DataIC50: 10nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175525BDBM175525(US9120744, CDE-001 (or 073))
Affinity DataIC50: 10nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92485BDBM92485(CDE-066 | US9120744, CDE-066)
Affinity DataIC50: 10nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175527BDBM175527(US9120744, CDE-003)
Affinity DataIC50: 10nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92482BDBM92482(CDE-008 | US9120744, CDE-008)
Affinity DataKd:  23nMpH: 5.0 T: 2°CAssay Description:To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92487BDBM92487(CDE-031 | US9120744, CDE-031)
Affinity DataKd:  31nMpH: 5.0 T: 2°CAssay Description:To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175546BDBM175546(US9120744, CDE-061)
Affinity DataIC50: 50nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175544BDBM175544(US9120744, CDE-058)
Affinity DataIC50: 50nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92484BDBM92484(CDE-056 | US9120744, CDE-056)
Affinity DataKd:  51nMpH: 5.0 T: 2°CAssay Description:To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92483BDBM92483(CDE-034 | US9120744, CDE-034)
Affinity DataKd:  67nMpH: 5.0 T: 2°CAssay Description:To establish binding constants for the compounds/drugs to PAI-1, an indirect approach using surface plasmon resonance (SPR) was employed. Varying con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175558BDBM175558(US9120744, CDE-075)
Affinity DataIC50: 70nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175548BDBM175548(US9120744, CDE-059)
Affinity DataIC50: 90nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92487BDBM92487(CDE-031 | US9120744, CDE-031)
Affinity DataIC50: 280nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92482BDBM92482(CDE-008 | US9120744, CDE-008)
Affinity DataIC50: 370nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92483BDBM92483(CDE-034 | US9120744, CDE-034)
Affinity DataIC50: 1.17E+3nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175552BDBM175552(US9120744, CDE-074)
Affinity DataIC50: 1.71E+3nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 92484BDBM92484(CDE-056 | US9120744, CDE-056)
Affinity DataIC50: 2.96E+3nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175534BDBM175534(US9120744, CDE-013)
Affinity DataIC50: 7.85E+3nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50310301BDBM50310301(N,N'-(ethane-1,2-diyl)bis(N-ethyl-3,4-dihydroxyben...)
Affinity DataIC50: 1.02E+4nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175542BDBM175542(US9120744, CDE-055)
Affinity DataIC50: 2.75E+4nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175537BDBM175537(US9120744, CDE-051)
Affinity DataIC50: 2.87E+4nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175549BDBM175549(US9120744, CDE-068)
Affinity DataIC50: 3.27E+4nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175553BDBM175553(US9120744, CDE-041)
Affinity DataIC50: 4.79E+4nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175557BDBM175557(US9120744, CDE-067)
Affinity DataIC50: 4.83E+4nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175531BDBM175531(US9120744, CDE-009)
Affinity DataIC50: 4.93E+4nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175551BDBM175551(US9120744, CDE-072)
Affinity DataIC50: 1.04E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175554BDBM175554(US9120744, CDE-035)
Affinity DataIC50: 1.46E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175545BDBM175545(US9120744, CDE-057)
Affinity DataIC50: 1.95E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175532BDBM175532(US9120744, CDE-012)
Affinity DataIC50: 1.96E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175538BDBM175538(US9120744, CDE-060)
Affinity DataIC50: 2.36E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175561BDBM175561(US9120744, CDE-033)
Affinity DataIC50: 2.46E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50058812BDBM50058812(N,N'-1,3-Propanediylbis(3,4,5-trihydroxybenzamide)...)
Affinity DataIC50: 2.69E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175547BDBM175547(US9120744, CDE-062)
Affinity DataIC50: 3.32E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175533BDBM175533(US9120744, CDE-011)
Affinity DataIC50: 3.38E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175535BDBM175535(US9120744, CDE-028)
Affinity DataIC50: 3.86E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175543BDBM175543(US9120744, CDE-065)
Affinity DataIC50: 4.23E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50310300BDBM50310300(N,N'-(ethane-1,2-diyl)bis(3,4-dihydroxybenzenesulf...)
Affinity DataIC50: 4.50E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175540BDBM175540(US9120744, CDE-069)
Affinity DataIC50: 5.62E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 50058816BDBM50058816(N,N'-1,2-Ethanediylbis(3,4,5-trihydroxybenzamide)H...)
Affinity DataIC50: 9.00E+5nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent

TargetPlasminogen activator inhibitor 1(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 175539BDBM175539(US9120744, CDE-064)
Affinity DataIC50: 2.20E+6nMpH: 7.8 T: 2°CAssay Description:To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details
US Patent