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TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249124BDBM249124(US9453038, 1)
Affinity DataEC50:  1.90nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249145BDBM249145(US9453038, 23)
Affinity DataEC50:  2.10nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249137BDBM249137(US9453038, 15)
Affinity DataEC50:  3.80nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249148BDBM249148(US9453038, 26)
Affinity DataEC50:  4.30nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249157BDBM249157(US9453038, 35)
Affinity DataEC50:  8.90nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249127BDBM249127(US9453038, 4)
Affinity DataEC50:  11.4nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249134BDBM249134(US9453038, 10)
Affinity DataEC50:  13.9nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249146BDBM249146(US9453038, 24)
Affinity DataEC50:  15.1nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249146BDBM249146(US9453038, 24)
Affinity DataEC50:  17.1nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249147BDBM249147(US9453038, 25)
Affinity DataEC50:  21nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249127BDBM249127(US9453038, 4)
Affinity DataEC50:  21.8nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249159BDBM249159(US9453038, 37)
Affinity DataEC50:  23.5nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249149BDBM249149(US9453038, 27)
Affinity DataEC50:  23.8nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249137BDBM249137(US9453038, 15)
Affinity DataEC50:  24.6nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249129BDBM249129(US9453038, 5)
Affinity DataEC50:  36.4nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249143BDBM249143(US9453038, 21)
Affinity DataEC50:  39.1nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249155BDBM249155(US9453038, 33)
Affinity DataEC50:  47.4nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249129BDBM249129(US9453038, 5)
Affinity DataEC50:  48nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249152BDBM249152(US9453038, 30)
Affinity DataEC50:  49.1nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249138BDBM249138(US9453038, 16)
Affinity DataEC50:  51.5nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249125BDBM249125(US9453038, 2)
Affinity DataEC50:  53.4nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249136BDBM249136(US9453038, 12)
Affinity DataEC50:  53.6nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249142BDBM249142(US9453038, 20)
Affinity DataEC50:  63.9nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249154BDBM249154(US9453038, 32)
Affinity DataEC50:  65.1nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249158BDBM249158(US9453038, 36)
Affinity DataEC50:  66.7nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249153BDBM249153(US9453038, 31)
Affinity DataEC50:  68.8nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249141BDBM249141(US9453038, 19)
Affinity DataEC50:  71.8nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249140BDBM249140(US9453038, 18)
Affinity DataEC50:  81nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249139BDBM249139(US9453038, 17)
Affinity DataEC50:  108nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249138BDBM249138(US9453038, 16)
Affinity DataEC50:  111nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249132BDBM249132(US9453038, 8)
Affinity DataEC50:  116nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249156BDBM249156(US9453038, 34)
Affinity DataEC50:  118nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249150BDBM249150(US9453038, 28)
Affinity DataEC50:  157nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249135BDBM249135(US9453038, 11)
Affinity DataEC50:  187nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249151BDBM249151(US9453038, 29)
Affinity DataEC50:  234nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249150BDBM249150(US9453038, 28)
Affinity DataEC50:  281nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249144BDBM249144(US9453038, 22)
Affinity DataEC50:  456nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249133BDBM249133(US9453038, 9)
Affinity DataEC50:  533nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249150BDBM249150(US9453038, 28)
Affinity DataEC50:  710nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249131BDBM249131(US9453038, 7)
Affinity DataEC50:  774nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249126BDBM249126(US9453038, 3)
Affinity DataEC50:  797nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 249151BDBM249151(US9453038, 29)
Affinity DataEC50:  1.97E+3nMT: 2°CAssay Description:To test the exemplified compounds, the following assay was employed. Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent