Compile Data Set for Download or QSAR
Report error Found 144 Enz. Inhib. hit(s) with all data for entry = 10362
TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530621BDBM530621(WO2022076495, EXAMPLE 65 | 1-(5-(difluoromethoxy)-...)
Affinity DataIC50: 0.700nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530630BDBM530630(WO2022076495, EXAMPLE 70a)
Affinity DataIC50: 1nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530622BDBM530622(WO2022076495, EXAMPLE 66a)
Affinity DataIC50: 1.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530640BDBM530640(WO2022076495, EXAMPLE 75a)
Affinity DataIC50: 1.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530624BDBM530624(WO2022076495, EXAMPLE 67a)
Affinity DataIC50: 1.60nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530556BDBM530556(WO2022076495, EXAMPLE 2 | 1-(3-(difluoromethoxy)ph...)
Affinity DataIC50: 1.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530627BDBM530627(WO2022076495, EXAMPLE 68b)
Affinity DataIC50: 1.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530648BDBM530648(WO2022076495, EXAMPLE 79 | 1-(5-(Difluoromethoxy)-...)
Affinity DataIC50: 2.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530557BDBM530557(WO2022076495, EXAMPLE 3)
Affinity DataIC50: 2.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530641BDBM530641(WO2022076495, EXAMPLE 75b)
Affinity DataIC50: 2.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530636BDBM530636(WO2022076495, EXAMPLE 73a)
Affinity DataIC50: 2.60nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530689BDBM530689(WO2022076495, EXAMPLE 120)
Affinity DataIC50: 3.20nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530637BDBM530637(WO2022076495, EXAMPLE 73b)
Affinity DataIC50: 3.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530629BDBM530629(WO2022076495, EXAMPLE 69b)
Affinity DataIC50: 3.90nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530684BDBM530684(WO2022076495, EXAMPLE 115 | l-(2-(2,2-difluoroetho...)
Affinity DataIC50: 4.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530626BDBM530626(WO2022076495, EXAMPLE 68a)
Affinity DataIC50: 4.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530563BDBM530563(WO2022076495, EXAMPLE 9)
Affinity DataIC50: 4.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530633BDBM530633(WO2022076495, EXAMPLE 71b)
Affinity DataIC50: 5.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530687BDBM530687(WO2022076495, EXAMPLE 118)
Affinity DataIC50: 5.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530644BDBM530644(WO2022076495, EXAMPLE 77a)
Affinity DataIC50: 5.60nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530651BDBM530651(WO2022076495, EXAMPLE 82)
Affinity DataIC50: 5.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530638BDBM530638(WO2022076495, EXAMPLE 74a)
Affinity DataIC50: 6.10nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530650BDBM530650(WO2022076495, EXAMPLE 81)
Affinity DataIC50: 6.30nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530634BDBM530634(WO2022076495, EXAMPLE 72a)
Affinity DataIC50: 6.40nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530639BDBM530639(WO2022076495, EXAMPLE 74b)
Affinity DataIC50: 6.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530635BDBM530635(WO2022076495, EXAMPLE 72b)
Affinity DataIC50: 6.60nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530569BDBM530569(WO2022076495, EXAMPLE 15)
Affinity DataIC50: 6.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530679BDBM530679(WO2022076495, EXAMPLE 110)
Affinity DataIC50: 7nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530649BDBM530649(WO2022076495, EXAMPLE 80)
Affinity DataIC50: 7.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530643BDBM530643(WO2022076495, EXAMPLE 76b)
Affinity DataIC50: 7.90nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530558BDBM530558(WO2022076495, EXAMPLE 4 | 3-(3-(difluoromethoxy)ph...)
Affinity DataIC50: 8.5nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530678BDBM530678(WO2022076495, EXAMPLE 109)
Affinity DataIC50: 9nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530628BDBM530628(WO2022076495, EXAMPLE 69a)
Affinity DataIC50: 9.70nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530645BDBM530645(WO2022076495, EXAMPLE 77b)
Affinity DataIC50: 9.80nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530599BDBM530599(WO2022076495, EXAMPLE 45a)
Affinity DataIC50: 12nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530677BDBM530677(WO2022076495, EXAMPLE 108 | 1-[3-(difluoromethoxy)...)
Affinity DataIC50: 12nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530647BDBM530647(WO2022076495, EXAMPLE 78b)
Affinity DataIC50: 13nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530568BDBM530568(WO2022076495, EXAMPLE 14)
Affinity DataIC50: 15nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530565BDBM530565(WO2022076495, EXAMPLE 11)
Affinity DataIC50: 15nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530561BDBM530561(WO2022076495, EXAMPLE 7)
Affinity DataIC50: 16nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530567BDBM530567(WO2022076495, EXAMPLE 13)
Affinity DataIC50: 17nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530623BDBM530623(WO2022076495, EXAMPLE 66b)
Affinity DataIC50: 17nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530590BDBM530590(WO2022076495, EXAMPLE 36)
Affinity DataIC50: 19nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530656BDBM530656(WO2022076495, EXAMPLE 87 | l-isopropyl-A-(4-methyl...)
Affinity DataIC50: 20nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530664BDBM530664(WO2022076495, EXAMPLE 95)
Affinity DataIC50: 23nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530579BDBM530579(WO2022076495, EXAMPLE 25 | 1-(3-(difluoromethoxy)p...)
Affinity DataIC50: 23nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530592BDBM530592(WO2022076495, EXAMPLE 38)
Affinity DataIC50: 24nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530662BDBM530662(WO2022076495, EXAMPLE 93)
Affinity DataIC50: 24nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530686BDBM530686(WO2022076495, EXAMPLE 117)
Affinity DataIC50: 27nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

TargetDiacylglycerol O-acyltransferase 2(Human)
Merck Sharp &Amp

WIPO
LigandChemical structure of BindingDB Monomer ID 530572BDBM530572(WO2022076495, EXAMPLE 18)
Affinity DataIC50: 28nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product 13Ci8-triolein (13C-l,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022076495

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