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Target
Thromboxane A2 receptor
Ligand
BDBM50283060
Substrate
n/a
Meas. Tech.
ChEBML_209743
EC50
58±n/a nM
Citation
 Burk, RM; Gac, TS; Garst, ME; Gibson, LL; Krauss, AH; Protzman, CE; Woodward, DF Synthesis of a novel series of 3-oxo-2,4-dioxobicyclo[3.2.1]octanes: additional evidence for two thromboxane receptor subtypes. Bioorg Med Chem Lett 4:2103-2106 (1994)    Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
TA2R_RAT | TXA2/PGH2 | Tbxa2r | Thromboxane A2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36943.05
Organism:
RAT
Description:
Thromboxane A2 TBXA2R RAT::P34978
Residue:
341
Sequence:
MWLNSTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAVVASQHAALLDWRATDPGCRLCHFMGAAMVFFGLCPLLLGAAMAAERFVGITRPFSRPAATSRRAWATVGLVWVGAGTLGLLPLLGLGRYSVQYPGSWCFLTLGAERGDVAFGLMFALLGSVSVGLSLLLNTVSVATLCRVYHAREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFILQTLLQTLPVMSPSGQLLRTTERQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFTSQLQAVSLHSPPTQAMLSGP
  
Inhibitor
Name:
BDBM50283060
Synonyms:
(Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-3-oxo-2,4-dioxa-bicyclo[3.2.1]oct-6-yl]-hept-5-enoic acid amide | CHEMBL441620
Type:
Small organic molecule
Emp. Form.:
C21H33NO5
Mol. Mass.:
379.4904
SMILES:
CCCCCC(O)\C=C\[C@H]1[C@H]2C[C@H](OC(=O)O2)[C@@H]1C\C=C/CCCC(N)=O
Structure:
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