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Target
Prostaglandin F2-alpha receptor
Ligand
BDBM323763
Substrate
n/a
Meas. Tech.
In Vitro Test of Inhibition of Human FP Receptor Activity (B-1A)
IC50
52.0±n/a nM
Citation
 Beck, H; Thaler, T; Kast, R; Meibom, D; Meininghaus, M; Terjung, C; Delbeck, M; Lustig, K; Muenster, U; Olenik, B Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents US Patent  US10189788 Publication Date 1/29/2019 
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor
Type:
Enzyme
Mol. Mass.:
40072.29
Organism:
Homo sapiens (Human)
Description:
P43088
Residue:
359
Sequence:
MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
  
Inhibitor
Name:
BDBM323763
Synonyms:
4-({[6-Bromo-2-(4-fluorophenyl)-3-methylquinolin-4-yl]carbonyl}amino)-3-fluorobenzoic acid | US10189788, Example 43
Type:
Small organic molecule
Emp. Form.:
C24H15BrF2N2O3
Mol. Mass.:
497.288
SMILES:
Cc1c(nc2ccc(Br)cc2c1C(=O)Nc1ccc(cc1F)C(O)=O)-c1ccc(F)cc1
Structure:
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