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Target
Chymotrypsinogen A
Ligand
BDBM50059013
Substrate
n/a
Meas. Tech.
ChEMBL_34106 (CHEMBL649735)
IC50
230±n/a nM
Citation
 Niwata, S; Fukami, H; Sumida, M; Ito, A; Kakutani, S; Saitoh, M; Suzuki, K; Imoto, M; Shibata, H; Imajo, S; Kiso, Y; Tanaka, T; Nakazato, H; Ishihara, T; Takai, S; Yamamoto, D; Shiota, N; Miyazaki, M; Okunishi, H; Kinoshita, A; Urata, H; Arakawa, K Substituted 3-(phenylsulfonyl)-1-phenylimidazolidine-2,4-dione derivatives as novel nonpeptide inhibitors of human heart chymase. J Med Chem 40:2156-63 (1997) [PubMed]  Article 
Target
Name:
Chymotrypsinogen A
Synonyms:
Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:
Serine protease
Mol. Mass.:
25670.88
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN
  
Inhibitor
Name:
BDBM50059013
Synonyms:
3-(4-Chloro-benzoyl)-1-phenyl-imidazolidine-2,4-dione | CHEMBL305296
Type:
Small organic molecule
Emp. Form.:
C16H11ClN2O3
Mol. Mass.:
314.723
SMILES:
Oc1cn(-c2ccccc2)c(=O)n1C(=O)c1ccc(Cl)cc1
Structure:
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