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Target
Nonstructural protein 3
Ligand
BDBM50514003
Substrate
n/a
Meas. Tech.
ChEMBL_1905417 (CHEMBL4407775)
IC50
380±n/a nM
Citation
 Rassias, G; Zogali, V; Swarbrick, CMD; Ki Chan, KW; Chan, SA; Gwee, CP; Wang, S; Kaplanai, E; Canko, A; Kiousis, D; Lescar, J; Luo, D; Matsoukas, MT; Vasudevan, SG Cell-active carbazole derivatives as inhibitors of the zika virus protease. Eur J Med Chem 180:536-545 (2019) [PubMed]  Article 
Target
Name:
Nonstructural protein 3
Synonyms:
Genome polyprotein | NS3
Type:
PROTEIN
Mol. Mass.:
7653.58
Organism:
Zika virus
Description:
ChEMBL_119671
Residue:
66
Sequence:
AETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMKRGDLPV
  
Inhibitor
Name:
BDBM50514003
Synonyms:
CHEMBL4437334
Type:
Small organic molecule
Emp. Form.:
C19H12Cl2N4O4
Mol. Mass.:
431.229
SMILES:
[O-][N+](=O)c1ccc(N\N=C2\C=CC(=O)C(=C2)C(=O)Nc2cccc(Cl)c2)c(Cl)c1 |c:10,14|
Structure:
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