Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 2
Ligand
BDBM391995
Substrate
n/a
Meas. Tech.
Biological Data
EC50
206±n/a nM
Citation
 Beard, RL; Duong, TT; Garst, ME Imidazole derivatives as formyl peptide receptor modulators US Patent  US10800744 Publication Date 10/13/2020 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM391995
Synonyms:
2-(2-{(1S)-2-methyl-1- [({[4-(trifluoromethyl) phenyl]amino}carbonyl) amino]propyl}-1H- imidazol-1-yl)-N- propylacetamide | US10301269, Number 41 | US10800744, Number 41
Type:
Small organic molecule
Emp. Form.:
C20H26F3N5O2
Mol. Mass.:
425.4479
SMILES:
CCCNC(=O)Cn1ccnc1[C@@H](NC(=O)Nc1ccc(cc1)C(F)(F)F)C(C)C |r|
Structure:
Search PDB for entries with ligand similarity: