Compile Data Set for Download or QSAR
Report error Found 609 for UniProtKB: P15206
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM139540(US8889696, Staurosporine | US9051313, Staurosporin...)
Affinity DataIC50: 2.63nMAssay Description:Compounds of the present disclosure were tested in a 10-dose IC50 mode with a 3-fold serial dilution starting from 0.5 μM, and the control compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2023
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5595(4-{[4-amino-6-(cyclohexylmethoxy)-5-nitrosopyrimid...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7478(CHEMBL23254 | 2-chloro-4-[(2-{[(2R)-1-hydroxy-3-me...)
Affinity DataIC50: 6nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-33P] ATP. 33...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5545(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}-N-m...)
Affinity DataIC50: 9nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7501(CHEMBL48362 | 4-{[(2Z)-4,6-dihydroxy-7-(1-methylpi...)
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence ATP/ [gamma-32P] ATP. 32P incorpo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5544(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benz...)
Affinity DataIC50: 9.5nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5544(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benz...)
Affinity DataIC50: 9.5nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM10642(CHEMBL83320 | 2-[({2-[(1-hydroxy-3-methylbutan-2-y...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM684220(US20240218021, Example 206)
Affinity DataIC50: 20nMAssay Description:FP binding assays were performed in 25 mM HEPES pH 7.5, 100 mM NaCl, 1 mM DTT, 0.01% NP-40 and 1 mg/mL BSA for all 3 protein complexes in black 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2024
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM683991(US20240218021, Example 438)
Affinity DataIC50: 20nMAssay Description:FP binding assays were performed in 25 mM HEPES pH 7.5, 100 mM NaCl, 1 mM DTT, 0.01% NP-40 and 1 mg/mL BSA for all 3 protein complexes in black 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2024
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM684472(US20240218021, Example 333)
Affinity DataIC50: 20nMAssay Description:FP binding assays were performed in 25 mM HEPES pH 7.5, 100 mM NaCl, 1 mM DTT, 0.01% NP-40 and 1 mg/mL BSA for all 3 protein complexes in black 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2024
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM683811(US20240218021, Example 348)
Affinity DataIC50: 20nMAssay Description:FP binding assays were performed in 25 mM HEPES pH 7.5, 100 mM NaCl, 1 mM DTT, 0.01% NP-40 and 1 mg/mL BSA for all 3 protein complexes in black 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2024
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM684383(US20240218021, Example 288)
Affinity DataIC50: 20nMAssay Description:FP binding assays were performed in 25 mM HEPES pH 7.5, 100 mM NaCl, 1 mM DTT, 0.01% NP-40 and 1 mg/mL BSA for all 3 protein complexes in black 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2024
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM684468(US20240218021, Example 331)
Affinity DataIC50: 20nMAssay Description:FP binding assays were performed in 25 mM HEPES pH 7.5, 100 mM NaCl, 1 mM DTT, 0.01% NP-40 and 1 mg/mL BSA for all 3 protein complexes in black 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2024
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7491(4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...)
Affinity DataIC50: 22nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7263(CHEMBL299756 | 9-oxo-8,18-diazatetracyclo[9.7.0.0^...)
Affinity DataIC50: 24nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7264(NSC 709125 | 4,5-dimethoxy-14-nitro-8,18-diazatetr...)
Affinity DataIC50: 24nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7492(3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2...)
Affinity DataIC50: 25nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750529(US20250195475, Example 181)
Affinity DataIC50: 34.4nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7262(NSC 705701 | BDBM84528 | alsterpaullone | 9-Nitrop...)
Affinity DataIC50: 35nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7265(NSC 708244 | 4,5-dimethoxy-9-oxo-8,18-diazatetracy...)
Affinity DataIC50: 44nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7269(CHEMBL121492 | 3-[9-oxo-14-(trifluoromethyl)-8,18-...)
Affinity DataIC50: 47nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7280(4-bromo-14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7...)
Affinity DataIC50: 53nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750373(US20250195475, Example 25)
Affinity DataIC50: 54.9nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750537(US20250195475, Example 189)
Affinity DataIC50: 58.6nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7500((2Z)-4,6-dihydroxy-7-(1-methylpiperidin-4-yl)-2-[(...)
Affinity DataIC50: 60nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence ATP/ [gamma-32P] ATP. 32P incorpo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7576(CHEMBL24484 | 2-purine deriv. 3a | 1-(6-{[(4-chlor...)
Affinity DataIC50: 60nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7576(CHEMBL24484 | 2-purine deriv. 3a | 1-(6-{[(4-chlor...)
Affinity DataIC50: 60nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7584(1-{6-[(3-chlorophenyl)amino]-9-(propan-2-yl)-9H-pu...)
Affinity DataIC50: 60nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750491(US20250195475, Example 143)
Affinity DataIC50: 60.9nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750484(US20250195475, Example 136)
Affinity DataIC50: 64.6nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5551(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benz...)
Affinity DataIC50: 67nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750528(US20250195475, Example 180)
Affinity DataIC50: 69.4nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5594(CHEMBL101801 | 4-{[4-amino-6-(cyclohexylmethoxy)-5...)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750445(US20250195475, Example 97)
Affinity DataIC50: 72.6nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750448(US20250195475, Example 100)
Affinity DataIC50: 74.8nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7339(NSC 719341 | 8-oxo-3-thia-7,17-diazatetracyclo[8.7...)
Affinity DataIC50: 75nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5546(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}-N,N...)
Affinity DataIC50: 77nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7340(13-nitro-3-thia-7,17-diazatetracyclo[8.7.0.0^{2,6}...)
Affinity DataIC50: 80nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5547(6-(cyclohexylmethoxy)-N-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 80nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7330(NSC 720310 | 4-methoxy-14-nitro-8,18-diazatetracyc...)
Affinity DataIC50: 80nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750470(US20250195475, Example 122)
Affinity DataIC50: 89.4nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5541(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}phen...)
Affinity DataIC50: 94nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750362(US20250195475, Example 14)
Affinity DataIC50: 96.7nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM10635(3-{[(2-{[1-(hydroxymethyl)-2-methylpropyl]amino}-9...)
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 100nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence ATP/ [gamma-32P] ATP. 32P incorpo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750539(US20250195475, Example 191)
Affinity DataIC50: 101nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
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TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM750372(US20250195475, Example 24)
Affinity DataIC50: 102nMAssay Description:Compound Preparation. Dissslove the compounds into DMSO solution to make 10 mM DMSO stock. Serially dilute the stock solution from highest concentrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM5549(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}-2-m...)
Affinity DataIC50: 103nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
Shengke Pharmaceuticals (Jiangsu)

US Patent
LigandPNGBDBM7498(CHEMBL51709 | (2Z)-2-benzylidene-4,6-dihydroxy-7-(...)
Affinity DataIC50: 110nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence ATP/ [gamma-32P] ATP. 32P incorpo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2006
Entry Details Article
PubMed
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