Compile Data Set for Download or QSAR
Report error Found 58 of affinity data for UniProtKB/TrEMBL: Q80Z39
LigandChemical structure of BindingDB Monomer ID 50384637BDBM50384637(CHEMBL2036951)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384641BDBM50384641(CHEMBL2036955)
Affinity DataEC50:  2nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50337038BDBM50337038(5-(3-cyclopropylpropyl)-2-(difluoromethyl)-3H-pyra...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384634BDBM50384634(CHEMBL2036948)
Affinity DataEC50:  4nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384640BDBM50384640(CHEMBL2036954)
Affinity DataEC50:  5nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50337024BDBM50337024(2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propy...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384616BDBM50384616(CHEMBL2036813)
Affinity DataEC50:  8nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50384612BDBM50384612(CHEMBL2036958)
Affinity DataEC50:  8nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50362630BDBM50362630(CHEMBL1939047)
Affinity DataEC50:  28nMAssay Description:Agonist activity at rat nicotinic acid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 23515BDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataKi:  33nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 23515BDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  39nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 23515BDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  39nMAssay Description:Agonist activity at rat GPR109aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50325899BDBM50325899(2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-on...)
Affinity DataEC50:  60nMAssay Description:Agonist activity at rat GPR109A receptor assessed as GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50220842BDBM50220842(3-butyl-1H-pyrazole-5-carboxylic acid | 5-butyl-1H...)
Affinity DataKi:  72nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50362632BDBM50362632(CHEMBL1939049)
Affinity DataEC50:  83nMAssay Description:Agonist activity at rat nicotinic acid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50325924BDBM50325924(2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at rat GPR109A receptor assessed as GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50220850BDBM50220850(3-propyl-1H-pyrazole-5-carboxylic acid | 5-propyl-...)
Affinity DataKi:  143nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50132140BDBM50132140(1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic...)
Affinity DataKi:  156nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50325913BDBM50325913(2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at rat GPR109A receptor assessed as GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50667388BDBM50667388(CHEMBL6188892)
Affinity DataEC50:  250nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50325899BDBM50325899(2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-on...)
Affinity DataIC50: 400nMAssay Description:Displacement of radioligand from rat GPR109AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50667389BDBM50667389(CHEMBL6190195)
Affinity DataEC50:  470nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50667390BDBM50667390(CHEMBL6189165)
Affinity DataEC50:  470nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50667391BDBM50667391(CHEMBL6189008)
Affinity DataEC50:  470nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50667392BDBM50667392(CHEMBL6190417)
Affinity DataEC50:  470nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50667393BDBM50667393(CHEMBL6189988)
Affinity DataEC50:  470nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50667394BDBM50667394(CHEMBL6190345)
Affinity DataEC50:  470nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50216550BDBM50216550(5-(3-Chloro-benzyl)-1H-pyrazole-3-carboxylic acid ...)
Affinity DataKi:  504nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50132132BDBM50132132(1H-pyrazole-3-carboxylic acid | CHEMBL128679)
Affinity DataKi:  594nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50325924BDBM50325924(2-((3-chlorophenethyloxy)methyl)pyrido[2,3-d]pyrim...)
Affinity DataIC50: 640nMAssay Description:Displacement of radioligand from rat GPR109AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 23515BDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataEC50:  670nMAssay Description:Agonist activity at rat GPR109A expressed by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50211363BDBM50211363(5-isopropyl-3-carboxyl-pyrazole | 5-Isopropyl-1H-p...)
Affinity DataKi:  683nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50667387BDBM50667387(CHEMBL6193583)
Affinity DataEC50:  1.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50667385BDBM50667385(CHEMBL6191466)
Affinity DataEC50:  1.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50462122BDBM50462122(CHEMBL4240407)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at rat GPR109A expressed in T-REx-CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50667386BDBM50667386(CHEMBL6189526)
Affinity DataEC50:  1.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50216537BDBM50216537(3-benzyl-1H-pyrazole-5-carboxylic acid | 5-Benzyl-...)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50462128BDBM50462128(CHEMBL4248415)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at rat GPR109A expressed in T-REx-CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50325913BDBM50325913(2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of radioligand from rat GPR109AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50132146BDBM50132146(5-Phenethyl-1H-pyrazole-3-carboxylic acid | CHEMBL...)
Affinity DataKi:  1.57E+3nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50325922BDBM50325922(2-((4-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at rat GPR109A receptor assessed as GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50462127BDBM50462127(CHEMBL4239086)
Affinity DataEC50:  2.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50462127BDBM50462127(CHEMBL4239086)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at rat GPR109A expressed in T-REx-CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50273099BDBM50273099(MK-0354 | 3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydroc...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity against rat GPR109a assessed as GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50325922BDBM50325922(2-((4-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...)
Affinity DataIC50: 2.70E+3nMAssay Description:Displacement of radioligand from rat GPR109AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50277582BDBM50277582(2-(3-(7-hydroxy-4,5-dihydropyrazolo[1,5-a]quinolin...)
Affinity DataEC50:  2.70E+3nMAssay Description:Agonist activity at rat GPR109A expressed by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50132142BDBM50132142(4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid |...)
Affinity DataKi:  3.54E+3nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50132144BDBM50132144(5-(4-Chloro-benzyl)-1H-pyrazole-3-carboxylic acid ...)
Affinity DataKi:  3.61E+3nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50313976BDBM50313976(2-({3-[3-(5-hydroxypyridin-2-yl)-1,2,4-oxadiazol-5...)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonist activity at rat GPR109A receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50132139BDBM50132139(5-(3-Phenyl-propyl)-1H-pyrazole-3-carboxylic acid ...)
Affinity DataKi:  6.30E+3nMAssay Description:Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
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