Compile Data Set for Download or QSAR
Report error Found 230 of affinity data for UniProtKB/TrEMBL: Q9UHP3
TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481952BDBM481952(US10913753, Compound I-19)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481951BDBM481951(US10913753, Compound I-18)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 478041BDBM478041(US10889592, Compound I-20)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481986BDBM481986(US10913753, Compound I-53)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481947BDBM481947(US10913753, Compound I-14)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 478042BDBM478042(US10889592, Compound I-21 | US11325917, Compound I...)
Affinity DataIC50: 200nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP25 Activity: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481981BDBM481981(US10913753, Compound I-48)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481998BDBM481998(US10913753, Compound I-65)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481997BDBM481997(US10913753, Compound I-64)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 554115BDBM554115(US11325917, Compound I-6)
Affinity DataIC50: 200nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP25 Activity: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482065BDBM482065(US10913753, Compound I-132)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481995BDBM481995(US10913753, Compound I-62)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482063BDBM482063(US10913753, Compound I-130)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482026BDBM482026(US10913753, Compound I-93 | US10913753, Compound I...)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481954BDBM481954(US10913753, Compound I-21)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481935BDBM481935(US10913753, Compound I-2)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482139BDBM482139(US10913753, Compound I-206)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482105BDBM482105(US10913753, Compound I-172 | US20230365583, Compou...)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481948BDBM481948(US10913753, Compound I-15 | US10913753, Compound I...)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482137BDBM482137(US10913753, Compound I-204)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481980BDBM481980(US10913753, Compound I-47)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482015BDBM482015(US10913753, Compound I-82)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481977BDBM481977(US10913753, Compound I-44)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482014BDBM482014(US10913753, Compound I-81)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481940BDBM481940(US10913753, Compound I-7)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 50279687BDBM50279687(CHEMBL4174196)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human His6-tagged USP25 expressed in baculovirus infected Sf21 insect cells using Ub-Rh110 as substrate pretreated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 478026BDBM478026(US10889592, Compound I-6)
Affinity DataIC50: 200nMAssay Description:USP25: The assay was performed in a final volume of 9 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 50279693BDBM50279693(CHEMBL4169696)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human His6-tagged USP25 expressed in baculovirus infected Sf21 insect cells using Ub-Rh110 as substrate pretreated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 50514121BDBM50514121(CHEMBL4442615)
Affinity DataIC50: 620nMAssay Description:Inhibition of USP25 (unknown origin) using Ub-Rho100 as substrate by calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 50608546BDBM50608546(CHEMBL5273364)
Affinity DataIC50: 880nMAssay Description:Inhibition of USP25 (unknown origin) using Ub-Rho100 as substrate by calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482095BDBM482095(US10913753, Compound I-162)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481953BDBM481953(US10913753, Compound I-20)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481949BDBM481949(US10913753, Compound I-16)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481948BDBM481948(US10913753, Compound I-15 | US10913753, Compound I...)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482088BDBM482088(US10913753, Compound I-155)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481946BDBM481946(US10913753, Compound I-13 | US20230365583, Compoun...)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482103BDBM482103(US10913753, Compound I-170)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482102BDBM482102(US10913753, Compound I-169)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481955BDBM481955(US10913753, Compound I-22)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481970BDBM481970(US10913753, Compound I-37)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482110BDBM482110(US10913753, Compound I-177)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481969BDBM481969(US10913753, Compound I-36)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482109BDBM482109(US10913753, Compound I-176)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481967BDBM481967(US10913753, Compound I-34)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482106BDBM482106(US10913753, Compound I-173)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482104BDBM482104(US10913753, Compound I-171)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482117BDBM482117(US10913753, Compound I-184)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482116BDBM482116(US10913753, Compound I-183)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 481974BDBM481974(US10913753, Compound I-41)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 25(Human)
Valo Early Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 482114BDBM482114(US10913753, Compound I-181)
Affinity DataIC50: 1.10E+3nMAssay Description:USP25: The assay was performed in a final volume of 9 uL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HC1, pH 8.0 solution; Corning 46...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent

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