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TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596365(CHEMBL5179810)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516992(CHEMBL4473371)
Affinity DataKi:  3.10nMAssay Description:Inhibition of AChE (unknown origin) by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516960(CHEMBL4435544)
Affinity DataIC50: 6nMAssay Description:Inhibition of AChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596366(CHEMBL5204683)
Affinity DataIC50: 12nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516959(CHEMBL4471876)
Affinity DataIC50: 27nMAssay Description:Inhibition of AChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596377(CHEMBL5181578)
Affinity DataIC50: 32nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596341(CHEMBL5176418)
Affinity DataIC50: 36nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 44nMAssay Description:Inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596380(CHEMBL5173121)
Affinity DataIC50: 44nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516976(CHEMBL4518438)
Affinity DataIC50: 47nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50459975(CHEMBL4228909)
Affinity DataIC50: 50nMAssay Description:Inhibition of nAChR epsilon (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516974(CHEMBL4516351)
Affinity DataIC50: 57nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596378(CHEMBL5207035)
Affinity DataIC50: 58nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516977(CHEMBL4518992)
Affinity DataIC50: 58nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516975(CHEMBL4514263)
Affinity DataIC50: 62nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596367(CHEMBL5190924)
Affinity DataIC50: 71nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516963(CHEMBL2376519)
Affinity DataIC50: 82nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596382(CHEMBL5188135)
Affinity DataIC50: 83nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596360(CHEMBL5200573)
Affinity DataIC50: 87nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516982(CHEMBL4447626)
Affinity DataIC50: 88nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596381(CHEMBL5179648)
Affinity DataIC50: 91nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516950(CHEMBL4544630)
Affinity DataIC50: 97nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596341(CHEMBL5176418)
Affinity DataKi:  120nMAssay Description:Mixed type inhibition of AChE (unknown origin) assessed as inhibitory constant by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50177174(9-amino-5,6,7,8-tetrahydroacridin-4yl)methano | CH...)
Affinity DataIC50: 125nMAssay Description:Inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567435(CHEMBL4872191)
Affinity DataIC50: 131nMAssay Description:Inhibition of human alpha1beta1deltaepsilon nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current respons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKi:  152nMAssay Description:Inhibition of AChE (unknown origin) by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596379(CHEMBL5196896)
Affinity DataIC50: 407nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50596361(CHEMBL5206933)
Affinity DataIC50: 676nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516970(CHEMBL4456791)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 10 secs measured at 30 s intervals for two minutes by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516985(CHEMBL4544034)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516966(CHEMBL4452517)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516965(CHEMBL4458943)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516964(CHEMBL4573754)
Affinity DataIC50: 6.37E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516989(CHEMBL4590975)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567433(CHEMBL4869892)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human alpha1beta1deltaepsilon nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current respons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit epsilon(Human)
Guizhou Medical University

Curated by ChEMBL
LigandPNGBDBM50516949(CHEMBL4555431)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232599(CHEMBL4095046)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232606(CHEMBL4083246)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232609(CHEMBL4098776)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232607(CHEMBL4063152)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232596(CHEMBL4064914)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232612(CHEMBL4098850)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232593(CHEMBL4087500)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232615(CHEMBL4091037)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232600(CHEMBL4074583)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232594(CHEMBL4102566)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232602(CHEMBL4097654)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50232613(CHEMBL4061082)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2019
Entry Details Article
PubMed
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