Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50032828
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335503(1-(4-(6-benzylthiazolo[4,5-b]pyridin-2-yl)-3-fluor...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335514(1-((3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,...)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human S1P5R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335505(1-((4-(5-benzylthiazolo[4,5-b]pyridin-2-yl)-3-fluo...)
Affinity DataEC50:  1.01E+4nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335506(1-(4-(6-benzylthiazolo[4,5-c]pyridin-2-yl)-3-fluor...)
Affinity DataEC50:  5.46E+3nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335507(1-((3-fluoro-4-(6-(1-phenylcyclopropyl)benzo[d]thi...)
Affinity DataEC50:  4.67E+3nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335508(1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  3.47E+3nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335509(1-((4-(6-benzylthiazolo[5,4-b]pyridin-2-yl)-3-fluo...)
Affinity DataEC50:  2.89E+3nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335510(1-(3-fluoro-4-(5-(2-phenylpropan-2-yl)thiazolo[5,4...)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335511(1-(3-fluoro-4-(5-(1-phenylcyclobutyl)thiazolo[5,4-...)
Affinity DataEC50:  1.31E+3nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335512(1-(4-(5-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  1.21E+3nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335513(1-((3-fluoro-4-(5-((R)-1-phenylethyl)thiazolo[5,4-...)
Affinity DataEC50:  996nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335514(1-((3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,...)
Affinity DataEC50:  888nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335515(1-((3-fluoro-4-(5-((S)-1-phenylethyl)thiazolo[5,4-...)
Affinity DataEC50:  877nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335516(1-((3-fluoro-4-(5-(1-phenylcyclohexyl)thiazolo[5,4...)
Affinity DataEC50:  836nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335517(1-(4-(5-benzylthiazolo[5,4-b]pyridin-2-yl)-3-fluor...)
Affinity DataEC50:  478nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335506(1-(4-(6-benzylthiazolo[4,5-c]pyridin-2-yl)-3-fluor...)
Affinity DataEC50:  3.98E+3nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335503(1-(4-(6-benzylthiazolo[4,5-b]pyridin-2-yl)-3-fluor...)
Affinity DataEC50:  1.60E+3nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335504(1-(4-(5-benzylthiazolo[5,4-c]pyridin-2-yl)-3-fluor...)
Affinity DataEC50:  429nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335508(1-(4-(6-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  221nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335517(1-(4-(5-benzylthiazolo[5,4-b]pyridin-2-yl)-3-fluor...)
Affinity DataEC50:  199nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335505(1-((4-(5-benzylthiazolo[4,5-b]pyridin-2-yl)-3-fluo...)
Affinity DataEC50:  144nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335509(1-((4-(6-benzylthiazolo[5,4-b]pyridin-2-yl)-3-fluo...)
Affinity DataEC50:  138nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335511(1-(3-fluoro-4-(5-(1-phenylcyclobutyl)thiazolo[5,4-...)
Affinity DataEC50:  119nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335512(1-(4-(5-benzylbenzo[d]thiazol-2-yl)-3-fluorobenzyl...)
Affinity DataEC50:  41nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335507(1-((3-fluoro-4-(6-(1-phenylcyclopropyl)benzo[d]thi...)
Affinity DataEC50:  38nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335513(1-((3-fluoro-4-(5-((R)-1-phenylethyl)thiazolo[5,4-...)
Affinity DataEC50:  38nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335515(1-((3-fluoro-4-(5-((S)-1-phenylethyl)thiazolo[5,4-...)
Affinity DataEC50:  35nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335516(1-((3-fluoro-4-(5-(1-phenylcyclohexyl)thiazolo[5,4...)
Affinity DataEC50:  33nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335510(1-(3-fluoro-4-(5-(2-phenylpropan-2-yl)thiazolo[5,4...)
Affinity DataEC50:  33nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335518(1-((3-fluoro-4-(5-(1-phenylcyclopentyl)thiazolo[5,...)
Affinity DataEC50:  26nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335514(1-((3-fluoro-4-(5-(1-phenylcyclopropyl)thiazolo[5,...)
Affinity DataEC50:  2nMAssay Description:Induction of human GFP-tagged chimeric S1P1R internalization in human U2Os cells by fluorescence microscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335504(1-(4-(5-benzylthiazolo[5,4-c]pyridin-2-yl)-3-fluor...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3R expressed in CHO cells by Ca(2+) mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed