BDBM26190 1,4-Dihydroxybenzene, XIII::1,4-dihydroxybenzene::CHEMBL537::Hydroquinone (9)::Hydroquinone, HQ::benzene-1,4-diol::phenol derivative, 4

SMILES Oc1ccc(O)cc1

InChI Key InChIKey=QIGBRXMKCJKVMJ-UHFFFAOYSA-N

Data  22 KI  16 IC50  1 ITC

PDB links: 11 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 26190   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Erzurum Technical University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition by Lineweaver-Bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  90nM ΔG°:  -9.61kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  90nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  100nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
TargetCarbonic anhydrase(Dicentrarchus labrax)
Gumushane University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  5.93E+3nMAssay Description:Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  7.80E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 3(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  8.20E+3nM ΔG°:  -6.93kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 15(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.06E+4nMAssay Description:Inhibition of mouse recombinant carbonic anhydrase 15 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.07E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.07E+4nM ΔG°:  -6.78kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.08E+4nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Agri Ibrahim Cecen University

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.08E+4nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Agri Ibrahim Cecen University

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.08E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.25E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.41E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  3.25E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  4.20E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  7.43E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  5.21E+5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  5.24E+5nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  8.83E+5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Gallus gallus (Chicken))
University Of Oulu

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataKi:  1.40E+7nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  4.50E+6nMAssay Description:Inhibition of mushroom tyrosinase activity after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  9.81E+3nMAssay Description:Inhibition of mushroom tyrosinase activity after 20 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  4.40E+6nMAssay Description:Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  4.21E+6nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  8.76E+4nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was monitored by dopachrome formation at 475nm for an appropriate period.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
National Tsing Hua University

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  1.88E+5nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was monitored by dopachrome formation at 475nm for an appropriate period.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate after 20 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  1.09E+6nMAssay Description:Inhibition of mushroom tyrosinase using as L-DOPA substrate after 2 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of mushroom tyrosinase using as L-tyrosine substrate after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  4.40E+6nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  4.40E+6nMAssay Description:Inhibition of human tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  4.50E+6nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  4.50E+6nMAssay Description:Inhibition of mushroom tyrosinase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 26190   

HostPNGBDBM36284(BDBM36303 | BDBM36310 | Methyl Viologen-Cucurbit[8...)
University Of Cambridge

GuestPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
ITC DataΔG°: -4.94kcal/mole logk: 4.20E+3
pH: 7.0 T: 25.00°C