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Report error Found 241 of affinity data for UniProtKB/TrEMBL: O43293
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  1nMAssay Description:Average Binding Constant for DAPK3; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  1nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50332294(N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)...)
Affinity DataKd:  1.20nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human ZIPK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human ZIPK using KKLNRTLSFAEPG as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human ZIPK using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50616768(CHEMBL5407013)
Affinity DataKi: >10nMAssay Description:Inhibition of human recombinant GST-fused DAPK3 (1 to 320 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant using MY...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50172243(CHEMBL3103192)
Affinity DataIC50: 10nMAssay Description:Inhibition of Dapk3 (unknown origin) at by quantitative PCRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  13nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50569979(CHEMBL4875028)
Affinity DataKd:  13nMAssay Description:Binding affinity to wild-type human partial length DAPK3 (M1 to A277 residues) expressed in bacterial expression system by measuring active site-dire...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human DAPK3 in presence of ATP at Km concentration by radiometric filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant DAPK3 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  22nMAssay Description:Binding affinity to DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  22nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  22nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  22nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50505542(CHEMBL4576489)
Affinity DataKd:  25nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DAPK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  41nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50505541(CHEMBL4465866)
Affinity DataKd:  41nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged DAPK3 (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  82nMAssay Description:Binding affinity to DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  82nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataKd:  89nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  100nMAssay Description:Binding constant for full-length DLKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50616767(CHEMBL5410656)
Affinity DataKi:  119nMAssay Description:Inhibition of human recombinant GST-fused DAPK3 (1 to 320 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant using MY...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50616766(CHEMBL5413882)
Affinity DataKi:  126nMAssay Description:Inhibition of human recombinant GST-fused DAPK3 (1 to 320 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant using MY...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd:  130nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50166251(CHEMBL3799389)
Affinity DataIC50: 140nMAssay Description:Inhibition of DAPK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314672(2-(3-bromophenyl)-4-(pyridin-3-ylmethylene)oxazol-...)
Affinity DataIC50: 148nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314673(2-(2-bromo-4-methoxyphenyl)-4-(pyridin-3-ylmethyle...)
Affinity DataIC50: 157nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  170nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  170nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)
Affinity DataKd:  170nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  190nMAssay Description:Binding constant for full-length DLKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314664(2-(2-chloro-5-iodophenyl)-4-(pyridin-4-ylmethylene...)
Affinity DataIC50: 227nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM104065(HS38)
Affinity DataKi:  260nMAssay Description:Inhibition of human recombinant GST-fused DAPK3 (1 to 320 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant using MY...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50554817(CHEMBL4764610)
Affinity DataIC50: 260nMAssay Description:Inhibition of human DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314670(2-(4-bromo-3-methylphenyl)-4-(pyridin-3-ylmethylen...)
Affinity DataIC50: 279nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314665(2-(4-chloro-3-nitrophenyl)-4-(pyridin-3-ylmethylen...)
Affinity DataIC50: 279nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM104065(HS38)
Affinity DataKd:  280nMAssay Description:Binding affinity to DAPK3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314671(2-(4-nitrophenyl)-4-(pyridin-3-ylmethylene)oxazol-...)
Affinity DataIC50: 291nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  300nMAssay Description:Average Binding Constant for DAPK3; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  300nMAssay Description:Inhibition of DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50355496(CHEMBL1908397)
Affinity DataKd:  310nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50616760(CHEMBL5433785)
Affinity DataIC50: 310nMAssay Description:Inhibition of DAPK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50616765(CHEMBL5425555)
Affinity DataKi:  315nMAssay Description:Inhibition of human recombinant GST-fused DAPK3 (1 to 320 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant using MY...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314668(2-(3,4-difluorophenyl)-4-(pyridin-3-ylmethylene)ox...)
Affinity DataIC50: 346nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314669(2-(3-chlorophenyl)-4-(pyridin-3-ylmethylene)oxazol...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Ambit Biosciences

Curated by ChEMBL
LigandPNGBDBM50314674(2-(3-methoxyphenyl)-4-(pyridin-3-ylmethylene)oxazo...)
Affinity DataIC50: 395nMAssay Description:Inhibition of human recombinant DAPK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
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