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Report error Found 269 of affinity data for UniProtKB/TrEMBL: P19525
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50405586(CHEMBL5279578)
Affinity DataEC50:  37nMAssay Description:Inhibition of PKR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308051(US9650366, 3 | US10011593, Ex. 3)
Affinity DataKi:  39nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308051(US9650366, 3 | US10011593, Ex. 3)
Affinity DataIC50: 39nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308056(US9650366, 6 | US10011593, Ex. 6)
Affinity DataIC50: 66nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308056(US9650366, 6 | US10011593, Ex. 6)
Affinity DataKi:  66nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM364980(US9868726, Example 5 | 6-amino-5-{5-[({[4-chloro-3...)
Affinity DataIC50: 69nMAssay Description:PKR: Commercially available recombinant human GST-PKR (1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2, 10 mM KCl, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM364980(US9868726, Example 5 | 6-amino-5-{5-[({[4-chloro-3...)
Affinity DataIC50: 69nMAssay Description:Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM364980(US9868726, Example 5 | 6-amino-5-{5-[({[4-chloro-3...)
Affinity DataIC50: 69nMAssay Description:Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308055(US9650366, 5 | US10011593, Ex. 5)
Affinity DataIC50: 76nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308055(US9650366, 5 | US10011593, Ex. 5)
Affinity DataKi:  76nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50637925(CHEMBL5559304)
Affinity DataIC50: 79nMAssay Description:Inhibition of PKR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308057(US9650366, 8 | US10011593, Ex. 8)
Affinity DataIC50: 82nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308057(US9650366, 8 | US10011593, Ex. 8)
Affinity DataKi:  82nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50405585(CHEMBL5286788)
Affinity DataEC50:  95nMAssay Description:Inhibition of PKR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50442163(CHEMBL2441346)
Affinity DataIC50: 99nMAssay Description:Inhibition of PKR (unknown origin) assessed as EIF2AK2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308054(US9650366, 4 | US10011593, Ex. 4)
Affinity DataKi:  99nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308054(US9650366, 4 | US10011593, Ex. 4)
Affinity DataIC50: 99nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50347891(CHEMBL1802629)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50347876(CHEMBL1802782)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 116nMAssay Description:Inhibition of PKR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  120nMAssay Description:Binding affinity to PRKRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50440018(CHEMBL2425628)
Affinity DataKd:  120nMAssay Description:Binding affinity to PRKR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  120nMAssay Description:Binding constant for PRKR kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308050(US9650366, 2 | US10011593, Ex. 2)
Affinity DataKi:  140nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308050(US9650366, 2 | US10011593, Ex. 2)
Affinity DataIC50: 140nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50347926(CHEMBL1802778)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308060(US9650366, 11 | US10011593, Ex. 11)
Affinity DataKi:  158nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308060(US9650366, 11 | US10011593, Ex. 11)
Affinity DataIC50: 158nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM364984(US9868726, Example 6 | 6-amino-N-[dimethyl(oxido)-...)
Affinity DataIC50: 167nMAssay Description:PKR: Commercially available recombinant human GST-PKR (1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2, 10 mM KCl, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM364984(US9868726, Example 6 | 6-amino-N-[dimethyl(oxido)-...)
Affinity DataIC50: 167nMAssay Description:Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM364984(US9868726, Example 6 | 6-amino-N-[dimethyl(oxido)-...)
Affinity DataIC50: 167nMAssay Description:Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50637646(CHEMBL5556210)
Affinity DataIC50: 180nMAssay Description:Inhibition of PKR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  180nMAssay Description:Binding constant for PRKR kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50466038(CHEMBL4281823)
Affinity DataIC50: 210nMAssay Description:Inhibition of recombinant human PKR (252 to end residues) using RSRSRSRSRSRSRS as substrate after 40 mins in presence of [gamma-33P]-ATP by scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50173832(4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylme...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50230828([5-(p-fluorophenyl)-2-ureido]thiophene-3-carboxami...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50396536(CHEMBL2171122)
Affinity DataIC50: 291nMAssay Description:Inhibition of PKR assessed as EIF2AK2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50347887(CHEMBL1802769)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant PKR autophosphorylation using poly[I:C] after 10 mins by luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308063(US9650366, 14 | US10011593, Ex. 14)
Affinity DataKi:  301nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM308063(US9650366, 14 | US10011593, Ex. 14)
Affinity DataIC50: 301nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50405583(CHEMBL5271785)
Affinity DataIC50: 306nMAssay Description:Inhibition of PKR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50442162(CHEMBL2441342)
Affinity DataIC50: 359nMAssay Description:Inhibition of PKR (unknown origin) assessed as EIF2AK2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  360nMAssay Description:Binding constant for PRKR kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  360nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2011
Entry Details
PCBioAssay
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  360nMAssay Description:Binding constant for PRKR kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50405584(CHEMBL5266620)
Affinity DataIC50: 364nMAssay Description:Inhibition of PKR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM365353(US9868726, Example 58 | 5-{5-[({[4-chloro-3- (trif...)
Affinity DataIC50: 390nMAssay Description:Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM365353(US9868726, Example 58 | 5-{5-[({[4-chloro-3- (trif...)
Affinity DataIC50: 390nMAssay Description:PKR: Commercially available recombinant human GST-PKR (1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2, 10 mM KCl, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM365353(US9868726, Example 58 | 5-{5-[({[4-chloro-3- (trif...)
Affinity DataIC50: 390nMAssay Description:Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2019
Entry Details
US Patent

TargetInterferon-induced, double-stranded RNA-activated protein kinase(Human)
Abbvie Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)
Affinity DataKd:  460nMAssay Description:Binding constant for PRKR kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
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