Affinity DataKi: 0.000590nMAssay Description:Displacement of [3H]DPCPX from human A1 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.000630nMAssay Description:Displacement of [3H]DPCPX from human A1 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.000740nMAssay Description:Displacement of [3H]DPCPX from human A1 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0295nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0400nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0400nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataKi: 0.0510nMAssay Description:Binding affinity to human adenosine A1A receptor measured by radioligand-based affinity assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0600nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataKi: 0.0760nMAssay Description:Binding affinity to human adenosine A1A receptor measured by radioligand-based affinity assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0800nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataKi: 0.0960nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]DPCPX from A1 adenosine receptor (unknown origin) expressed in CHO cell membrane incubated for 60 mins at room temperature by NXT...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of [3H]DPCPX from human A1 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for...More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Agonist activity at adenosine A1 receptor (unknown origin) expressed in CHO cells assessed as increase in intracellular cAMP level by RIAMore data for this Ligand-Target Pair
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at human A1A adenosine receptor expressed in HEK cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Agonist activity at adenosine A1 receptor assessed as inhibition of isoproterenol-stimulated cAMP accumulation in DDT1MF-2 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.123nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for...More data for this Ligand-Target Pair
Affinity DataEC50: 0.132nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Agonist activity at human A1A adenosine receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP production after 60 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.141nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for...More data for this Ligand-Target Pair
Affinity DataKi: 0.145nMAssay Description:All test compounds were prepared as a stock solution of 10 mM in 100% DMSO.Inhibition binding assays were performed using 2.5 μg of membranes pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.162nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKd: 0.170nMAssay Description:Binding affinity to human adenosine A1 receptor assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in HEK293 cells after 60 mins by rapid filtration assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.190nMAssay Description:Compound was evaluated for the Adenosine A1 receptor agonist potency.More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in HEK293 cells assessed as reduction in CPA-mediated inhibition of forskolin-stimulated...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
Affinity DataIC50: 0.209nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 0.240nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for...More data for this Ligand-Target Pair
