48 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Cmpds
Data
Article Title
Organization
26
Thiazolo[3,2-a]benzimidazol-3(2H)-one derivatives: Structure-activity relationships of selective nucleotide pyrophosphatase/phosphodiesterase1 (NPP1) inhibitors.
University of Bonn
25
Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.
Sanford-Burnham Medical Research Institute
17
Imidazopyridine- and purine-thioacetamide derivatives: potent inhibitors of nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1).
Ku Leuven
6
Highly potent and selective ectonucleotide pyrophosphatase/phosphodiesterase I inhibitors based on an adenosine 5'-(a or¿)-thio-(a,ß- orß,¿)-methylenetriphosphate scaffold.
Bar-Ilan University
7
Nonhydrolyzable ATP analogues as selective inhibitors of human NPP1: a combined computational/experimental study.
UniversitÉ
5
Diadenosine 5',5''-(boranated)polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors.
Bar-Ilan University
8
1,3,4-Oxadiazole-2(3H)-thione and its analogues: a new class of non-competitive nucleotide pyrophosphatases/phosphodiesterases 1 inhibitors.
University of Karachi
34
Discovery of orally bioavailable phosphonate prodrugs of potent ENPP1 inhibitors for cancer treatment.
Haihe Biopharma
31
Design, Synthesis, and Pharmacological Evaluation of Quinazoline and Quinoline Derivatives as Potent ENPP1 Inhibitors for Cancer Immunotherapy.
Shanghai Jiao Tong University
16
Advances in CD73 inhibitors for immunotherapy: Antibodies, synthetic small molecule compounds, and natural compounds.
Chengdu University of Traditional Chinese Medicine
36
Discovery of Imidazo[1,2-a]pyrazine Derivatives as Potent ENPP1 Inhibitors.
Shanghai Institute of Materia Medica
38
[1,2,4]Triazolo[1,5-a]pyrimidine derivatives: Structure-activity relationship study leading to highly selective ENPP1 inhibitors.
Nagoya City University
29
Discovery of Pyrido[2,3-d]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment.
Shanghai Institute of Materia Medica
24
Insight into small-molecule inhibitors targeting extracellular nucleotide pyrophosphatase/phosphodiesterase1 for potential multiple human diseases.
Sichuan University
36
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 inhibitors: Research progress and prospects.
China Pharmaceutical University
28
Discovery of Orally Bioavailable Phthalazinone Analogues as an ENPP1 Inhibitor for STING-Mediated Cancer Immunotherapy.
Ajou University
6
Design and synthesis of new adamantyl derivatives as promising antiproliferative agents.
University of Sharjah
19
Discovery of 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one and 3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one derivatives as novel ENPP1 inhibitors.
Korea Institute of Science and Technology
14
Synthesis, biological evaluation, and docking studies of novel pyrrolo[2,3-b]pyridine derivatives as both ectonucleotide pyrophosphatase/phosphodiesterase inhibitors and antiproliferative agents.
Comsats University Islamabad
11
Synthesis of biphenyl oxazole derivatives via Suzuki coupling and biological evaluations as nucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors.
Quaid-I-Azam University
42
Targeting Metabolism of Extracellular Nucleotides via Inhibition of Ectonucleotidases CD73 and CD39.
Arcus Biosciences
23
Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry.
X-Chem
34
Synthesis, biological evaluation, and molecular docking study of sulfonate derivatives as nucleotide pyrophosphatase/phosphodiesterase (NPP) inhibitors.
University of Sharjah
5
Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold.
Bar-Ilan University
10
Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase.
University of Sharjah
23
Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile.
Quaid-I-Azam University
3
Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-P
Bar-Ilan University
19
Synthesis and biological evaluation of novel quinazoline-4-piperidinesulfamide derivatives as inhibitors of NPP1.
Laval University
14
Chemoselective synthesis and biological evaluation of arylated 2-(Trifluoromethyl) quinolines as nucleotide pyrophosphatase (NPPs) inhibitors.
Universit£T Rostock
37
Quinoxalinone compounds, compositions, methods, and kits for increasing genome editing efficiency
Vertex Pharmaceuticals
147
GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF
Tiger Biotherapeutics
45
Imidazo[1,2-c]pyrimidine derivatives as PRC2 inhibitors for treating cancer
Mirati Therapeutics
12
3-ARYLOXYL-3-FIVE-MEMBERED HETEROARYL PROPYLAMINE COMPOUND AND USE THEREOF
Shanghai Leado Pharmatech Co.
6
COMPOUND AS TYK2/JAK1 PSEUDOKINASE DOMAIN INHIBITOR, AND SYNTHESIS AND USE METHODS
Zhejiang Wenda Pharmaceutical Technology
63
IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Shanghai Leadingtac Pharmaceutical
2
N-heterocyclic five-membered ring-containing capsid protein assembly inhibitor, pharmaceutical composition thereof, and use thereof
Chia Tai Tianqing Pharmaceutical Group
1
QUINOLINE COMPOUNDS
Guangzhou Baiyunshan Pharmaceutical Holdings Co., Ltd. Baiyunshan Pharmaceutical General Factory
234
6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors
Ajax Therapeutics
227
Condensed ring compounds having dopamine D3 receptor antagonistic effect
Shionogi
34
2,6-dioxaspiro [4,5] decane derivatives and preparation method therefor and pharmaceutical applications thereof
Shandong Luye Pharmaceutical Co.