BDBM13216 BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::US20230348453, Compound A8::cid_3062316::med.21724, Compound Dasatinib
SMILES Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1
InChI Key InChIKey=ZBNZXTGUTAYRHI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 13216
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of The Max Planck Society
Chemical Genomics Centre of The Max Planck Society
Affinity DataKd: 495nMAssay Description:Serine/threonine kinase inhibition assay using MAP p38 alpha fluorescence-labeled approach.More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of The Max Planck Society
Chemical Genomics Centre of The Max Planck Society
Affinity DataKd: 230nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of The Max Planck Society
Chemical Genomics Centre of The Max Planck Society
Affinity DataKd: 27nMAssay Description:Binding affinity to P38-alpha (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of The Max Planck Society
Chemical Genomics Centre of The Max Planck Society
Affinity DataKd: 230nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of The Max Planck Society
Chemical Genomics Centre of The Max Planck Society
Affinity DataKd: 27nMAssay Description:Binding constant for p38-alpha kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of The Max Planck Society
Chemical Genomics Centre of The Max Planck Society
Affinity DataKd: 230nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of The Max Planck Society
Chemical Genomics Centre of The Max Planck Society
Affinity DataKd: 27nMAssay Description:Binding constant for full-length p38-alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chemical Genomics Centre of The Max Planck Society
Chemical Genomics Centre of The Max Planck Society
Affinity DataEC50: 470nMAssay Description:Inhibition of recombinant Nanoluc-tagged p38alpha (unknown origin) expressed in HEK293 cells incubated for 2 to 3 mins by NanoBRET assayMore data for this Ligand-Target Pair