BDBM13216 BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::US20230348453, Compound A8::cid_3062316::med.21724, Compound Dasatinib
SMILES Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1
InChI Key InChIKey=ZBNZXTGUTAYRHI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 13216
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of LCK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of SRC (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of ABL1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of BRK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CSK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of LCK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Lyn B (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of SRC (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CSK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 6(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of BRK (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of ABL1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
University Of Silesia In Katowice
Curated by ChEMBL
University Of Silesia In Katowice
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair