BDBM13216 BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::US20230348453, Compound A8::cid_3062316::med.21724, Compound Dasatinib
SMILES Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1
InChI Key InChIKey=ZBNZXTGUTAYRHI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 13216
TargetTyrosine-protein kinase Blk(Mus musculus)
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse BLKMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetEphrin type-B receptor 2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetLIM domain kinase 1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant BtkMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant Abl kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 297nMAssay Description:Inhibition of recombinant Tec kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of TAP-tagged wild-type BtkMore data for this Ligand-Target Pair