BDBM50346243 CHEMBL1779593::furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)methanone::rac-furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)methanone

SMILES Oc1ccccc1C1CC(=NN1C(=O)c1ccco1)c1cccnc1

InChI Key InChIKey=WIYFQNKIVFKELN-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50346243   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase ICK(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed