BDBM50346243 CHEMBL1779593::furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)methanone::rac-furan-2-yl(5-(2-hydroxyphenyl)-3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)methanone

SMILES Oc1ccccc1C1CC(=NN1C(=O)c1ccco1)c1cccnc1

InChI Key InChIKey=WIYFQNKIVFKELN-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50346243   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase ICK(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LCK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KIT2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Chk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50346243(CHEMBL1779593 | furan-2-yl(5-(2-hydroxyphenyl)-3-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed