BDBM18355 (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol::CHEMBL1029::MIGLUSTAT::N-Butyl-DNJ::US20230339856, Compound NB-DNJ::US9181184, 5
SMILES CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
InChI Key InChIKey=UQRORFVVSGFNRO-UTINFBMNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 18355
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii
Curated by ChEMBL
University Of Napoli Federico Ii
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
University Of Napoli Federico Ii
Curated by ChEMBL
University Of Napoli Federico Ii
Curated by ChEMBL
Affinity DataIC50: 1.18E+5nMAssay Description:Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measur...More data for this Ligand-Target Pair