BDBM18860 (2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid::(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid::3,5,3'-triiodo-L-thyronine (T3)::CHEMBL1544::Triiodothyronine::Triiodothyronine (T3)::US10544075, Compound T3::[125I]T3::liothyronine::triothyrone
SMILES N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O
InChI Key InChIKey=AUYYCJSJGJYCDS-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 18860
Affinity DataKd: 0.0580nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
Affinity DataKd: 0.0810nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
Affinity DataKd: 0.0580nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
Affinity DataKd: 0.0810nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
Affinity DataKd: 0.170nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
Affinity DataKd: 0.140nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR beta 1)More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
Affinity DataKd: 0.100nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
Affinity DataKd: 0.0600nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
Affinity DataKd: 0.0870nMAssay Description:Binding affinity of compound was determined against thyroid hormone receptor beta 1More data for this Ligand-Target Pair
Affinity DataKd: 0.0580nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
Affinity DataKd: 0.0810nMAssay Description:Displacement of [125I]T3 from human TRbeta receptorMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataKd: 710nMAssay Description:Binding affinity to recombinant PPARgamma LBD (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair