BDBM18860 (2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid::(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid::3,5,3'-triiodo-L-thyronine (T3)::CHEMBL1544::Triiodothyronine::Triiodothyronine (T3)::US10544075, Compound T3::[125I]T3::liothyronine::triothyrone

SMILES N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O

InChI Key InChIKey=AUYYCJSJGJYCDS-LBPRGKRZSA-N

Data  11 KI  20 IC50  13 Kd  31 EC50

PDB links: 14 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18860   

TargetProthrombin(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at GST-labelled THRbeta ( 202 to 461 residues) (unknown origin) incubated for 2 hrs in presence SRC1-2 co-activator peptide by Alpha...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataEC50:  6.20nMAssay Description:Agonist activity at human THRbeta expressed in CHO cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human THRbeta expressed in green monkey CV1 cells after 24 hrs by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed