BDBM20880 (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol::BMS-512148::C-aryl glucoside, 6::CHEMBL429910::Dapagliflozin
SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
InChI Key InChIKey=JVHXJTBJCFBINQ-ADAARDCZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 20880
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Haisco Pharmaceuticals Group
Curated by ChEMBL
Haisco Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Haisco Pharmaceuticals Group
Curated by ChEMBL
Haisco Pharmaceuticals Group
Curated by ChEMBL
Affinity DataIC50: 629nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as decrease in uptake of [14C]AMG after 120 mins by TopCount methodMore data for this Ligand-Target Pair