BDBM20880 (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(hydroxymethyl)oxane-3,4,5-triol::BMS-512148::C-aryl glucoside, 6::CHEMBL429910::Dapagliflozin
SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1
InChI Key InChIKey=JVHXJTBJCFBINQ-ADAARDCZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 20880
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of human SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Guangdong Pharmaceutical University
Curated by ChEMBL
Guangdong Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair