BDBM28700 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic acid::2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoic acid::CHEMBL981::FENOFIBRIC ACID::FIBRICOR::Fenofibrate::LF 153::alpha-1081::procetofenic acid

SMILES CC(C)(Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1)C(O)=O

InChI Key InChIKey=MQOBSOSZFYZQOK-UHFFFAOYSA-N

Data  7 KI  15 IC50  15 Kd  33 EC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 28700   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50:  6.80E+4nMAssay Description:Binding affinity towards human peroxidase proliferator activated receptor alpha (hPPARalpha)More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibitory activity against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataEC50:  1.30E+4nMAssay Description:Cotransfection activity of compound against human Peroxisome proliferator activated receptor alpha was determinedMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataEC50: >1.00E+4nMAssay Description:Mean effective concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataEC50:  2.65E+3nMAssay Description:Activity at human PPARalpha in CV1 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]2-methyl-2-(4-{3-propyl-(5-pyridin-2yl-thiophene-2-sulfonyl)-amino]-pro-pyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of tritium labeled ligand from human PPARalpha by SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataEC50: >1.00E+4nMAssay Description:Displacement of tritium labeled ligand from human PPARalpha by SPA assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM28700(2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropionic a...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of tritium labeled ligand from human PPARgamma by SPA assayMore data for this Ligand-Target Pair