BDBM50069989 (R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butylboronic acid::(R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-6-carboxamido)propanamido)butylboronic acid::BORTEZOMIB::CHEMBL325041::Dipeptidyl boronic acid derivative::LDP-341::N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE::PS-341::Peptidyl boronic acid derivative::US11542283, Compound Velcade::Velcade::cid_387447
SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O
InChI Key InChIKey=GXJABQQUPOEUTA-RDJZCZTQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50069989
Affinity DataIC50: 78nMAssay Description:Inhibition of beta5i subunit of immunoproteasome (unknown origin) by active-site ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of caspase-like activity of human 20S proteasome using Ac-nLPnLD-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of beta5 subunit of immunoproteasome (unknown origin) by active-site ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Ac-RLR-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant cathepsin B (unknown origin) using Z-Leu-Arg-AMC as substrate by spectrofluorometer analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant cathepsin G (unknown origin) using Suc-Ala-Ala-Pro-Phe-AMC as substrate by spectrofluorometer analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of recombinant cathepsin A (unknown origin) using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH as substrate incubated with enzyme for 5...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit using Ac-RLR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit using Ac-nLPnLD-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair